symbyax
Symbyax is a combination medicine containing Fluoxetine Hydrochloride and Olanzapine.
Fluoxetine Hydrochloride and Olanzapine · by Lilly
Available as a generic: Olanzapine and Fluoxetine Hydrochloride
Key facts
- Active ingredient
- Fluoxetine Hydrochloride and Olanzapine
- Form
- Capsule
- Strength
- Fluoxetine Hydrochloride EQ 25MG Base; Olanzapine EQ 12MG Base **Federal Register Determination That Product was not Discontinued or Withdrawn for Safety or Effectiveness reasons** · Fluoxetine Hydrochloride EQ 25MG Base; Olanzapine EQ 3MG Base **Federal Register Determination That Product was not Discontinued or Withdrawn for Safety or Effectiveness reasons** · Fluoxetine Hydrochloride EQ 25MG Base; Olanzapine EQ 6MG Base **Federal Register Determination That Product was not Discontinued or Withdrawn for Safety or Effectiveness reasons** · Fluoxetine Hydrochloride EQ 50MG Base; Olanzapine EQ 12MG Base **Federal Register Determination That Product was not Discontinued or Withdrawn for Safety or Effectiveness reasons** · Fluoxetine Hydrochloride EQ 50MG Base; Olanzapine EQ 6MG Base **Federal Register Determination That Product was not Discontinued or Withdrawn for Safety or Effectiveness reasons**
- Type
- Prescription (Rx)
- Brand or generic
- Brand-name
- Manufacturer
- Lilly
- Half-life
- about 1 to 3 days (roughly 24-72 hours) after a single dose, lengthening to about 4 to 6 days with ongoing daily use (how long it stays in your system)
- What the pharmacy pays
- ~$0.05 per ml — not your price
- FDA application
- NDA021520
- Availability
- Discontinued (per FDA)
How long does Fluoxetine Hydrochloride and Olanzapine stay in your body?
The elimination half-life of fluoxetine hydrochloride and olanzapine is about 1 to 3 days (roughly 24-72 hours) after a single dose, lengthening to about 4 to 6 days with ongoing daily use — the time it takes the body to clear about half of it. As a rule of thumb, a medicine is mostly gone after roughly 4 to 5 half-lives, though this varies from person to person with age and kidney or liver function. Fluoxetine's active metabolite norfluoxetine has a much longer elimination half-life of about 4 to 16 days, so the drug clears from the body very slowly (over weeks); half-lives are also longer in people with liver cirrhosis (fluoxetine roughly 7-8 days vs 2-3 days normally).
This is general information, not medical advice. It doesn’t tell you when a drug test would read negative (tests detect substances for different, often longer, windows) or when it’s safe to take another dose — ask your pharmacist or prescriber. Source: PROZAC- fluoxetine hydrochloride capsule (DailyMed).
Dosage forms
Capsule
The forms currently marketed in the U.S., per the FDA National Drug Code Directory.
Ways to save
Ask for the generic
Same active ingredient, far cheaper. Is there a generic? →
Request a 90-day supply
Bulk fills usually lower the per-dose price vs monthly refills.
Use copay cards
Manufacturer copay cards & patient-assistance programs — especially for brand drugs.
Compare alternatives
A same-class option may cost less. See alternatives →
Frequently asked questions
- How much does Symbyax cost?
- Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $0.05 per ml, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins.
- Is there a coupon or discount for Symbyax?
- pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Symbyax. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
- Who makes Symbyax?
- Symbyax is marketed by Lilly. You can see Lilly's full profile, rating, and other products on pharmaranks.
- Is Symbyax a brand-name or generic drug?
- Symbyax is a brand-name product with the active ingredient Fluoxetine Hydrochloride and Olanzapine. Lower-cost generic equivalents containing Fluoxetine Hydrochloride and Olanzapine are available — ask your pharmacist.
- Is Symbyax available over the counter?
- No. Symbyax is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
- What forms does Symbyax come in?
- Symbyax is currently marketed as capsule, per the FDA's National Drug Code Directory.
- Is Symbyax FDA-registered?
- Symbyax is on record with the U.S. FDA under application number NDA021520. You can verify this on its official FDA label.
Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.
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