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sulfamethoxazole and trimethoprim double strength

Sulfamethoxazole and Trimethoprim Double Strength is a combination medicine containing Sulfamethoxazole and Trimethoprim.

Sulfamethoxazole and Trimethoprim · by Heritage Pharma Avet

Generic of Bactrim Ds

Not yet rated· sourced from the FDA label
Rated against independent regulatory sources·Last updated June 7, 2026·How we rate
Verified againstopenFDANIH DailyMedRxClass

Key facts

Active ingredient
Sulfamethoxazole and Trimethoprim
Form
Tablet
Strength
Sulfamethoxazole 800MG; Trimethoprim 160MG
Type
Prescription (Rx)
Brand or generic
Generic
Half-life
about 10 hours (how long it stays in your system)
FDA application
ANDA070037
Availability
Discontinued (per FDA)

How long does Sulfamethoxazole and Trimethoprim stay in your body?

The elimination half-life of sulfamethoxazole and trimethoprim is about 10 hours — the time it takes the body to clear about half of it. As a rule of thumb, a medicine is mostly gone after roughly 4 to 5 half-lives, though this varies from person to person with age and kidney or liver function. The FDA label states the mean serum half-life of sulfamethoxazole is 10 hours (co-formulated with trimethoprim, whose half-life is 8 to 10 hours). Half-life is prolonged in patients with severely impaired renal function, requiring dosage adjustment; the elderly, who often have reduced kidney function, may also clear it more slowly. Sulfamethoxazole is not a prodrug; it is partly metabolized to an inactive N-acetylated metabolite that does not outlast the parent. Half-life is not the same as a drug-test detection window — the drug can remain detectable longer than a single half-life implies.

This is general information, not medical advice. It doesn’t tell you when a drug test would read negative (tests detect substances for different, often longer, windows) or when it’s safe to take another dose — ask your pharmacist or prescriber. Source: DailyMed - Sulfamethoxazole and Trimethoprim Tablet (FDA label).

Dosage forms

Tablet

The forms currently marketed in the U.S., per the FDA National Drug Code Directory.

Ways to save

Ask for the generic

Same active ingredient, far cheaper. Is there a generic? →

Request a 90-day supply

Bulk fills usually lower the per-dose price vs monthly refills.

Use copay cards

Manufacturer copay cards & patient-assistance programs — especially for brand drugs.

Compare alternatives

A same-class option may cost less. See alternatives →

Frequently asked questions

Is there a coupon or discount for Sulfamethoxazole and Trimethoprim Double Strength?
pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Sulfamethoxazole and Trimethoprim Double Strength. To pay less, Sulfamethoxazole and Trimethoprim Double Strength is already a generic — usually the lowest-cost version — so the main levers are comparing cash prices between pharmacies and using a pharmacy discount-card service. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
Who makes Sulfamethoxazole and Trimethoprim Double Strength?
Sulfamethoxazole and Trimethoprim Double Strength is marketed by Heritage Pharma Avet. You can see Heritage Pharma Avet's full profile, rating, and other products on pharmaranks.
Is Sulfamethoxazole and Trimethoprim Double Strength a brand-name or generic drug?
Sulfamethoxazole and Trimethoprim Double Strength is a generic medication; its active ingredient is Sulfamethoxazole and Trimethoprim. Generics contain the same active ingredient as the brand-name original and are usually lower cost.
Is Sulfamethoxazole and Trimethoprim Double Strength available over the counter?
No. Sulfamethoxazole and Trimethoprim Double Strength is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
What forms does Sulfamethoxazole and Trimethoprim Double Strength come in?
Sulfamethoxazole and Trimethoprim Double Strength is currently marketed as tablet, per the FDA's National Drug Code Directory.
Is Sulfamethoxazole and Trimethoprim Double Strength FDA-registered?
Sulfamethoxazole and Trimethoprim Double Strength is on record with the U.S. FDA under application number ANDA070037. You can verify this on its official FDA label.

Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.

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