sohonos
Sohonos (Palovarotene) is a retinoid used to treat Heterotopic Ossification.
Palovarotene · by Ipsen
Key facts
- Active ingredient
- Palovarotene
- Drug class
- Retinoid
- Form
- Capsule
- Strength
- Palovarotene 1.5MG · Palovarotene 10MG · Palovarotene 1MG · Palovarotene 2.5MG · Palovarotene 5MG
- Type
- Prescription (Rx)
- Brand or generic
- Brand-name
- May treat
- heterotopic ossification
- Manufacturer
- Ipsen
- FDA application
- NDA215559
Storing Sohonos, and how long it keeps
Quoted from this product’s own FDA label. Storage belongs to the product and its device, not to the drug in general — a pen and a tablet of the same medicine are kept completely differently.
- “SOHONOS must be kept in the original carton to protect from light.”
Drug class
How this class works, per Tretinoin - StatPearls - NCBI Bookshelf.
May treat (source: NIH RxClass)
Dosage forms
Capsule
The forms currently marketed in the U.S., per the FDA National Drug Code Directory.
Ways to save
Ask for the generic
Same active ingredient, far cheaper. Is there a generic? →
Request a 90-day supply
Bulk fills usually lower the per-dose price vs monthly refills.
Use copay cards
Manufacturer copay cards & patient-assistance programs — especially for brand drugs.
Compare alternatives
A same-class option may cost less. See alternatives →
Frequently asked questions
- What does Sohonos treat?
- Sohonos (Palovarotene) may be used to treat heterotopic ossification, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.
- How does Sohonos work?
- Sohonos is a retinoid. Retinoids are vitamin A derivatives that enter skin cells and switch on retinoic acid receptors in the nucleus, which changes how genes are read. This normalizes how skin cells grow and shed, unclogs pores, calms inflammation, and over time boosts collagen production.
- Is there a coupon or discount for Sohonos?
- pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Sohonos. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
- Who makes Sohonos?
- Sohonos is marketed by Ipsen. You can see Ipsen's full profile, rating, and other products on pharmaranks.
- Is Sohonos a brand-name or generic drug?
- Sohonos is a brand-name product with the active ingredient Palovarotene.
- Is Sohonos available over the counter?
- No. Sohonos is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
- What forms does Sohonos come in?
- Sohonos is currently marketed as capsule, per the FDA's National Drug Code Directory.
- What class of drug is Sohonos?
- Sohonos is classified as retinoid, per the FDA's Established Pharmacologic Class.
- Is Sohonos FDA-registered?
- Sohonos is on record with the U.S. FDA under application number NDA215559. You can verify this on its official FDA label.
Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.
What people report to the FDA about PALOVAROTENE
The FDA Adverse Event Reporting System (FAERS) collects reports from patients and clinicians. It holds 16 reports naming PALOVAROTENE — the active ingredient in Sohonos, and the FDA flagged 94% of those reports as serious. The effects reported most often — leaving out reports about overdose, misuse or the condition being treated, which dominate the raw list for common medicines:
- cross sensitivity reaction4 reports
- alopecia3 reports
- dyspepsia3 reports
- nausea3 reports
- pruritus3 reports
- skin exfoliation3 reports
- dry skin2 reports
- pain in extremity2 reports
Read these as a signal, not a rate. A report does not mean PALOVAROTENE caused the effect — anyone can file one, and many describe people taking several medicines for several conditions. Crucially there is no denominator: FAERS does not record how many people took the drug, so these counts cannot be turned into “X% of patients” — a bigger number often just means a more widely used or more talked-about drug. Duplicates exist, and publicity drives reporting. For what is actually established, read the FDA label.
Source: openFDA drug/event (FAERS), retrieved September 25, 2026.
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