sodium iodide i 123
Sodium Iodide I 123 (Sodium Iodide I-123) is a medication supplied as a capsule, gelatin coated.
Sodium Iodide I-123 · by Ge Healthcare
Key facts
- Active ingredient
- Sodium Iodide I-123
- Form
- Capsule
- Strength
- Sodium Iodide I-123 100uCi · Sodium Iodide I-123 200uCi · Sodium Iodide I-123 2mCi/ML **Federal Register Determination That Product was not Discontinued or Withdrawn for Safety or Effectiveness reasons**
- Type
- Prescription (Rx)
- Brand or generic
- Brand-name
- Manufacturer
- Ge Healthcare
- FDA application
- NDA017630
- Availability
- Discontinued (per FDA)
What is Sodium Iodide I 123?
From the FDA label:Sodium Iodide I 123 (Na 123 I) for diagnostic use is supplied in capsules for oral administration. The capsules are available in strengths of 3.7 and 7.4 megabecquerels (MBq) (100 and 200 μCi) I-123 at time of calibration. The radionuclidic composition at calibration is not less than 97.0 percent I-123, not more than 2.9 percent I-125 and not more than 0.1 percent Te-121. The radionuclidic composition at expiration time is not less than 87.2 percent I-123, not more than 12.4 percent I-125 and not more than 0.4 percent Te-121. The ratio of the concentration of I-123 and I-125 changes with time. Graph 1 shows the minimum concentration of I-123 as a function of time and Graph 2 shows the maximum concentration of I-125 as a function of time. Graph 1. Radionuclidic Concentration of I-123 PERCENT OF TOTAL RADIOACTIVITY: IODINE-123 Graph 2. Radionuclidic Concentration of I-125 PERCENT OF TOTAL RADIOACTIVITY: IODINE-125 Graph 1 Graph 2 Physical Characteristics Iodine-123 decays by electron capture with a physical half-life of 13.2 hours Kocher, David C., Radioactive Decay Data Tables. DOE/TIC-11026, 122 (1981). . The photon that is useful for detection and imaging studies is listed in Table 1. Table 1. Principal Radiation Emission Data Radiation Mean % Disintegration Energy (keV) Gamma-2 83.4 159 External Radiation The specific gamma ray constant for I-123 is 1.6 R/hr-mCi at 1 cm. The…
How to use
The recommended oral dose for the average patient (70 kg) is 3.7 to 14.8 MBq (100 to 400 μCi). The lower part of the dosage range 3.7 MBq (100 μCi) is recommended for uptake studies alone, and the higher part 14.8 MBq (400 μCi) for thyroid imaging. The determination of I-123 concentration in the thyroid gland may be initiated at six hours after administering the dose and should be measured in accordance with standardized procedures. The patient dose should be measured by a suitable radioactivity calibration system immediately prior to administration. The capsules can be utilized up to 30 hours after calibration time and date. Thereafter, discard the capsules in accordance with standard safety procedures. The user should wear waterproof gloves at all times when handling the capsules or container. Radiation Dosimetry The estimated absorbed radiation doses to several organs of an average patient (70 kg) from oral administration of the maximum dose of 14.8 MBq (400 μCi) of I-123 are shown in Table 4 for thyroid uptakes of 5, 15, and 25%. For comparison at these three values of thyroid uptake, the estimated radiation doses from doses of 3.7 MBq (100 μCi) I-131, also used as thyroid imaging agent, are also included. Table 4. Absorbed Radiation Dose Estimates as a Function of Maximum Thyroid Uptake for Sodium Iodide I-123 * at Time of Calibration and Expiry Compared to Sodium Iodide…
Side effects
Although rare, reactions associated with the administration of sodium iodide isotopes for diagnostic use include, in decreasing order of frequency, nausea, vomiting, chest pain, tachycardia, itching skin, rash and hives.
Warnings
Important safety information
Females of childbearing age and pediatric patients should not be studied unless the benefits anticipated from the performance of the test outweigh the possible risk of exposure to the amount of ionizing radiation associated with the test.
Who should not take Sodium Iodide I 123
To date there are no known contraindications to the use of Sodium Iodide I 123 Capsules.
Dosage forms
Capsule
The forms currently marketed in the U.S., per the FDA National Drug Code Directory.
Ways to save
Ask for the generic
Same active ingredient, far cheaper. Is there a generic? →
Request a 90-day supply
Bulk fills usually lower the per-dose price vs monthly refills.
Use copay cards
Manufacturer copay cards & patient-assistance programs — especially for brand drugs.
Compare alternatives
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Frequently asked questions
- Is there a coupon or discount for Sodium Iodide I 123?
- pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Sodium Iodide I 123. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
- Who makes Sodium Iodide I 123?
- Sodium Iodide I 123 is marketed by Ge Healthcare. You can see Ge Healthcare's full profile, rating, and other products on pharmaranks.
- Is Sodium Iodide I 123 a brand-name or generic drug?
- Sodium Iodide I 123 is a brand-name product with the active ingredient Sodium Iodide I-123.
- Is Sodium Iodide I 123 available over the counter?
- No. Sodium Iodide I 123 is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
- What forms does Sodium Iodide I 123 come in?
- Sodium Iodide I 123 is currently marketed as capsule, per the FDA's National Drug Code Directory.
- Is Sodium Iodide I 123 FDA-registered?
- Sodium Iodide I 123 is on record with the U.S. FDA under application number NDA017630. You can verify this on its official FDA label.
- Is Sodium Iodide I 123 safe?
- There's no single safe-or-not verdict, and we don't yet have a composite recall-safety score for Sodium Iodide I 123. Review its FDA-label side effects and warnings below, and always consult a licensed professional.
- What are the side effects of Sodium Iodide I 123?
- Sodium Iodide I 123's side effects are taken directly from its FDA label. From the label: Although rare, reactions associated with the administration of sodium iodide isotopes for diagnostic use include, in decreasing order of frequency, nausea, vomiting, chest pain, tachycardia, itching skin, rash and hives. Both common and serious reactions are documented in full on this page. This is general reference from the FDA, not medical advice — always consult a professional.
Clinical content sourced from the FDA label via openFDA (U.S. FDA). View the FDA label on DailyMed → Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.
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