Skip to content
ppharmaranks
Menu

seasonale

Seasonale is a combination medicine containing Ethinyl Estradiol and Levonorgestrel.

Ethinyl Estradiol and Levonorgestrel · by Teva Branded Pharm

Available as a generic: Levonorgestrel and Ethinyl Estradiol

Not yet rated· sourced from the FDA label
Rated against independent regulatory sources·Last updated June 7, 2026·How we rate
Verified againstopenFDANIH DailyMedRxClass

Key facts

Active ingredient
Ethinyl Estradiol and Levonorgestrel
Form
Kit
Strength
Ethinyl Estradiol 0.03MG; Levonorgestrel 0.15MG
Type
Prescription (Rx)
Brand or generic
Brand-name
Manufacturer
Teva Branded Pharm
Half-life
about 36 hours (36 ± 13 hours at steady state) (how long it stays in your system)
FDA application
NDA021544

How long does Ethinyl Estradiol and Levonorgestrel stay in your body?

The elimination half-life of ethinyl estradiol and levonorgestrel is about 36 hours (36 ± 13 hours at steady state) — the time it takes the body to clear about half of it. As a rule of thumb, a medicine is mostly gone after roughly 4 to 5 half-lives, though this varies from person to person with age and kidney or liver function. This is the terminal elimination half-life stated directly for levonorgestrel; the label reports no active metabolite that outlasts the parent, and levonorgestrel is not a prodrug. The number comes from a levonorgestrel/ethinyl estradiol combination oral-contraceptive label (Aviane), where it is attributed specifically to the levonorgestrel component; the single-ingredient OTC emergency-contraceptive labels do not state a half-life. On populations: the label says no formal studies evaluated hepatic or renal impairment, but cautions that steroid hormones may be poorly metabolized in patients with impaired liver function; it notes no apparent pharmacokinetic differences across races, and states nothing about older adults.

This is general information, not medical advice. It doesn’t tell you when a drug test would read negative (tests detect substances for different, often longer, windows) or when it’s safe to take another dose — ask your pharmacist or prescriber. Source: Aviane (levonorgestrel and ethinyl estradiol) label — DailyMed, Clinical Pharmacology / Pharmacokinetics.

Dosage forms

Kit

The forms currently marketed in the U.S., per the FDA National Drug Code Directory.

Ways to save

Ask for the generic

Same active ingredient, far cheaper. Is there a generic? →

Request a 90-day supply

Bulk fills usually lower the per-dose price vs monthly refills.

Use copay cards

Manufacturer copay cards & patient-assistance programs — especially for brand drugs.

Compare alternatives

A same-class option may cost less. See alternatives →

Frequently asked questions

Is there a coupon or discount for Seasonale?
pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Seasonale. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
Who makes Seasonale?
Seasonale is marketed by Teva Branded Pharm. You can see Teva Branded Pharm's full profile, rating, and other products on pharmaranks.
Is Seasonale a brand-name or generic drug?
Seasonale is a brand-name product with the active ingredient Ethinyl Estradiol and Levonorgestrel. Lower-cost generic equivalents containing Ethinyl Estradiol and Levonorgestrel are available — ask your pharmacist.
Is Seasonale available over the counter?
No. Seasonale is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
What forms does Seasonale come in?
Seasonale is currently marketed as kit, per the FDA's National Drug Code Directory.
Is Seasonale FDA-registered?
Seasonale is on record with the U.S. FDA under application number NDA021544. You can verify this on its official FDA label.

Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.

What people report to the FDA about ETHINYL ESTRADIOL AND LEVONORGESTREL

The FDA Adverse Event Reporting System (FAERS) collects reports from patients and clinicians. It holds 91 reports naming ETHINYL ESTRADIOL AND LEVONORGESTREL — the active ingredient in Seasonale, and the FDA flagged 92% of those reports as serious. The effects reported most often — leaving out reports about overdose, misuse or the condition being treated, which dominate the raw list for common medicines:

  • drug exposure during pregnancy9 reports
  • nausea8 reports
  • vomiting8 reports
  • pregnancy on oral contraceptive7 reports
  • abdominal pain6 reports
  • pruritus6 reports
  • cytolytic hepatitis5 reports
  • asthenia4 reports

Read these as a signal, not a rate. A report does not mean ETHINYL ESTRADIOL AND LEVONORGESTREL caused the effect — anyone can file one, and many describe people taking several medicines for several conditions. Crucially there is no denominator: FAERS does not record how many people took the drug, so these counts cannot be turned into “X% of patients” — a bigger number often just means a more widely used or more talked-about drug. Duplicates exist, and publicity drives reporting. For what is actually established, read the FDA label.

Source: openFDA drug/event (FAERS), retrieved September 25, 2026.

Reviews

No reviews yet. Be the first to write one.

Write a review

Reviews are user opinions, not medical advice. Consult a licensed professional.

People also viewed

Compare Seasonale head-to-head

Identify a pill by its imprint →Check a drug interaction →Drug recalls →

Browse medications A–Z

Research products from A to Z, compare independent ratings, and find alternatives.