reglan

How long does Metoclopramide Hydrochloride stay in your body?

The elimination half-life of metoclopramide hydrochloride is about 5 to 6 hours — the time it takes the body to clear about half of it. As a rule of thumb, a medicine is mostly gone after roughly 4 to 5 half-lives, though this varies from person to person with age and kidney or liver function. This is the average elimination (terminal) half-life in adults with normal renal function; the label gives it as a 5-to-6-hour range and reports no separate distribution-phase figure. Metoclopramide is not a prodrug, and the FDA label does not describe an active metabolite that outlasts the parent — about half of the drug recovered in urine is excreted as free or conjugated (inactive) metoclopramide. Kidney impairment is the population the label singles out: as creatinine clearance falls, plasma, renal and non-renal clearance all fall and the elimination half-life lengthens, so the drug accumulates unless the maintenance dose is reduced. The label does not state a separate adult half-life for older adults or for liver impairment. It does note that in newborns the half-life is much longer (23.1 hours after a first dose in a 3.5-week-old infant) because of immature liver and kidney function, while in older children it is roughly 4 to 4.5 hours. Half-life describes how fast the drug leaves the blood — it is not a drug-test detection window (metabolites are detectable far longer) and not dosing guidance.

This is general information, not medical advice. It doesn’t tell you when a drug test would read negative (tests detect substances for different, often longer, windows) or when it’s safe to take another dose — ask your pharmacist or prescriber. Source: Metoclopramide Oral Solution — FDA label, Clinical Pharmacology / Pharmacokinetics (DailyMed SPL).

Frequently asked questions

What does Reglan treat?

Reglan (Metoclopramide Hydrochloride) may be used to treat gastroesophageal reflux, gastroparesis, postoperative nausea and vomiting, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.

How much does Reglan cost?

Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $1.34 for 30, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins.

Is there a coupon or discount for Reglan?

pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Reglan. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.

Who makes Reglan?

Reglan is marketed by Robins Ah. You can see Robins Ah's full profile, rating, and other products on pharmaranks.

Is Reglan a brand-name or generic drug?

Reglan is a brand-name product with the active ingredient Metoclopramide Hydrochloride. Lower-cost generic equivalents containing Metoclopramide Hydrochloride are available — ask your pharmacist.

Is Reglan available over the counter?

No. Reglan is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.

What forms does Reglan come in?

Reglan is currently marketed as tablet, per the FDA's National Drug Code Directory.

What class of drug is Reglan?

Reglan is classified as dopamine-2 receptor antagonist, per the FDA's Established Pharmacologic Class.

Is Reglan FDA-registered?

Reglan is on record with the U.S. FDA under application number NDA018821. You can verify this on its official FDA label.