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quinapril hydrochloride and hydrochlorothiazide

Quinapril Hydrochloride and Hydrochlorothiazide is a combination medicine containing Hydrochlorothiazide and Quinapril Hydrochloride.

Hydrochlorothiazide and Quinapril Hydrochloride · by Pharmobedient

Not yet rated· sourced from the FDA label
Rated against independent regulatory sources·Last updated June 7, 2026·How we rate
Verified againstopenFDANIH DailyMedRxClass

Key facts

Active ingredient
Hydrochlorothiazide and Quinapril Hydrochloride
Form
Tablet
Strength
Hydrochlorothiazide 12.5MG; Quinapril Hydrochloride EQ 10MG Base · Hydrochlorothiazide 12.5MG; Quinapril Hydrochloride EQ 20MG Base · Hydrochlorothiazide 25MG; Quinapril Hydrochloride EQ 20MG Base
Type
Prescription (Rx)
Brand or generic
Generic
Manufacturer
Pharmobedient
Half-life
about 6 to 15 hours (the label reports a range, not a single number) (how long it stays in your system)
What the pharmacy pays
~$0.91 for 30 — not your price
FDA application
ANDA077093
Availability
Discontinued (per FDA)

How long does Hydrochlorothiazide and Quinapril Hydrochloride stay in your body?

The elimination half-life of hydrochlorothiazide and quinapril hydrochloride is about 6 to 15 hours (the label reports a range, not a single number) — the time it takes the body to clear about half of it. As a rule of thumb, a medicine is mostly gone after roughly 4 to 5 half-lives, though this varies from person to person with age and kidney or liver function. This is the plasma ELIMINATION half-life. Plasma levels fall bi-exponentially: other FDA labels for hydrochlorothiazide combination products describe a distribution phase of roughly 2 hours before the ~10-hour (6-15 h) elimination phase — the elimination figure is the one given here. Hydrochlorothiazide is NOT a prodrug and is NOT metabolized, so there is no active metabolite that outlasts the parent; more than 95% of the absorbed dose is excreted unchanged in urine. Kidney impairment: the label states plainly that in patients with renal disease plasma concentrations are increased and the elimination half-life is PROLONGED — it does not quantify by how much. The label does not state a different half-life for older adults or for liver impairment, so no number should be assumed for those groups. Absorption (not elimination) is reduced in congestive heart failure. This is a pharmacokinetic figure about how long the drug stays in plasma; it is not a drug-test detection window and not dosing guidance.

This is general information, not medical advice. It doesn’t tell you when a drug test would read negative (tests detect substances for different, often longer, windows) or when it’s safe to take another dose — ask your pharmacist or prescriber. Source: DailyMed — HYDROCHLOROTHIAZIDE capsule, Clinical Pharmacology (Pharmacokinetics and Metabolism).

Dosage forms

Tablet

The forms currently marketed in the U.S., per the FDA National Drug Code Directory.

Ways to save

Ask for the generic

Same active ingredient, far cheaper. Is there a generic? →

Request a 90-day supply

Bulk fills usually lower the per-dose price vs monthly refills.

Use copay cards

Manufacturer copay cards & patient-assistance programs — especially for brand drugs.

Compare alternatives

A same-class option may cost less. See alternatives →

Frequently asked questions

How much does Quinapril Hydrochloride and Hydrochlorothiazide cost?
Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $0.91 for 30, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins.
Is there a coupon or discount for Quinapril Hydrochloride and Hydrochlorothiazide?
pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Quinapril Hydrochloride and Hydrochlorothiazide. To pay less, Quinapril Hydrochloride and Hydrochlorothiazide is already a generic — usually the lowest-cost version — so the main levers are comparing cash prices between pharmacies and using a pharmacy discount-card service. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
Who makes Quinapril Hydrochloride and Hydrochlorothiazide?
Quinapril Hydrochloride and Hydrochlorothiazide is marketed by Pharmobedient. You can see Pharmobedient's full profile, rating, and other products on pharmaranks.
Is Quinapril Hydrochloride and Hydrochlorothiazide a brand-name or generic drug?
Quinapril Hydrochloride and Hydrochlorothiazide is a generic medication; its active ingredient is Hydrochlorothiazide and Quinapril Hydrochloride. Generics contain the same active ingredient as the brand-name original and are usually lower cost.
Is Quinapril Hydrochloride and Hydrochlorothiazide available over the counter?
No. Quinapril Hydrochloride and Hydrochlorothiazide is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
What forms does Quinapril Hydrochloride and Hydrochlorothiazide come in?
Quinapril Hydrochloride and Hydrochlorothiazide is currently marketed as tablet, per the FDA's National Drug Code Directory.
Is Quinapril Hydrochloride and Hydrochlorothiazide FDA-registered?
Quinapril Hydrochloride and Hydrochlorothiazide is on record with the U.S. FDA under application number ANDA077093. You can verify this on its official FDA label.

Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.

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