pramosone

What is Pramosone?

From the FDA label:Analpram HC ® Lotion 2.5% is a topical preparation containing hydrocortisone acetate 2.5% w/w and pramoxine hydrochloride 1% w/w in a hydrolipid lotion base containing stearic acid, cetyl alcohol, FORLAN-L (Contains: petrolatum, lanolin, hydrogenated coconut oil, sorbitan sesquioleate, stearyl alcohol, and cetyl alcohol), glycerin, trolamine, polyoxyl 40 stearate, di-isopropyl adipate, povidone, dimethicone, potassium sorbate, sorbic acid, and purified water. Topical corticosteroids are anti-inflammatory and anti-pruritic agents. The structural formula, the chemical name, molecular formula and molecular weight for active ingredients are presented below: hydrocortisone acetate Pregn-4-ene-3, 20-dione, 21-(acetyloxy)-11, 17-dihydroxy-, (11-beta)- C 23 H 32 O 6 ; mol. wt.: 404.50 pramoxine hydrochloride 4-(3-(p-butoxyphenoxy)propyl)morpholine hydrochloride C 17 H 27 NO 3 .HCl ; mol. wt.: 329.87 hydrocortisone acetate pramoxine hydrochloride

How to use

Side effects

Who should not take Pramosone

Overdose — what happens if you take too much

How long does Hydrocortisone Acetate and Pramoxine Hydrochloride stay in your body?

The elimination half-life of hydrocortisone acetate and pramoxine hydrochloride is about 1.5 hours — the time it takes the body to clear about half of it. As a rule of thumb, a medicine is mostly gone after roughly 4 to 5 half-lives, though this varies from person to person with age and kidney or liver function. This is the plasma (terminal) elimination half-life; the FDA label states "The terminal half-life of hydrocortisone is about 1.5 hours following intravenous and oral dosing of hydrocortisone tablets" in healthy adults, so roughly 90% of a dose clears within about 8 hours and nearly all within ~12 hours. Hydrocortisone is not a prodrug, but its half-life measures how fast the drug leaves the blood, not how long its effects last: as a short-acting glucocorticoid its biological (tissue) effect on the body persists well beyond blood clearance, and this short plasma half-life is why oral replacement is usually dosed 2-3 times a day. Because hydrocortisone is metabolized in the liver, significant liver impairment can slow clearance; the label does not give a specific half-life adjustment for age, kidney, or liver function. Half-life is not the same as a drug-test detection window.

This is general information, not medical advice. It doesn’t tell you when a drug test would read negative (tests detect substances for different, often longer, windows) or when it’s safe to take another dose — ask your pharmacist or prescriber. Source: ALKINDI SPRINKLE (hydrocortisone) oral granules — FDA prescribing information, DailyMed.

Frequently asked questions

How much does Pramosone cost?

Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $0.15 per gm, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins.

Is there a coupon or discount for Pramosone?

pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Pramosone. To pay less, Pramosone is already a generic — usually the lowest-cost version — so the main levers are comparing cash prices between pharmacies and using a pharmacy discount-card service. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.

Who makes Pramosone?

Pramosone is marketed by Legacy Pharma. You can see Legacy Pharma's full profile, rating, and other products on pharmaranks.

Is Pramosone a brand-name or generic drug?

Pramosone is a generic medication; its active ingredient is Hydrocortisone Acetate and Pramoxine Hydrochloride. Generics contain the same active ingredient as the brand-name original and are usually lower cost.

Is Pramosone available over the counter?

No. Pramosone is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.

What forms does Pramosone come in?

Pramosone is currently marketed as topical, per the FDA's National Drug Code Directory.

Is Pramosone FDA-registered?

Pramosone is on record with the U.S. FDA under application number ANDA085979. You can verify this on its official FDA label.

Is Pramosone safe?

There's no single safe-or-not verdict, and we don't yet have a composite recall-safety score for Pramosone. Review its FDA-label side effects and warnings below, and always consult a licensed professional.

What are the side effects of Pramosone?

Pramosone's side effects are taken directly from its FDA label. From the label: The following local adverse reactions are reported infrequently with topical corticosteroids, but may occur more frequently with the use of occlusive dressings.… Both common and serious reactions are documented in full on this page. This is general reference from the FDA, not medical advice — always consult a professional.