plegisol in plastic container

What is Plegisol in Plastic Container?

From the FDA label:Plegisol (Cardioplegic Solution) is a sterile, nonpyrogenic, essentially isotonic, formulation of electrolytes in water for injection. It is a "core solution" intended for use only after addition of sodium bicarbonate to adjust pH prior to administration. After buffering with sodium bicarbonate it is suitable for cardiac instillation (usually with hypothermia) to induce arrest during open heart surgery. Other agents may be added to the solution prior to instillation (See INSTRUCTIONS FOR USE ). Each 100 mL of solution contains calcium chloride, dihydrate 17.6 mg, magnesium chloride, hexahydrate 325.3 mg, potassium chloride 119.3 mg and sodium chloride 643 mg in water for injection. May contain HCl or NaOH for pH adjustment. Electrolyte content per liter (not including ions for pH adjustment): Calcium (Ca ++ ) 2.4 mEq; magnesium (Mg ++ ) 32 mEq; potassium (K + ) 16 mEq; sodium (Na + ) 110 mEq; chloride (Cl‾) 160 mEq. Osmolar concentration, 304 mOsmol/liter (calc.); pH 3.8 (3.5 to 3.9) prior to sodium bicarbonate addition. It is required that 10 mL (840 mg) of 8.4% Sodium Bicarbonate Injection, USP (10 mEq each of sodium and bicarbonate) be added aseptically and thoroughly mixed with each 1000 mL of cardioplegic solution to adjust pH. Use 10 mL of Hospira List 4900, 8.4% Sodium Bicarbonate Injection, USP, to achieve the approximate pH of 7.8 when measured at room temperature.…

How to use

Side effects

Warnings

Who should not take Plegisol in Plastic Container

Overdose — what happens if you take too much

Interactions

Frequently asked questions

How is Plegisol in Plastic Container rated?

pharmaranks gives Plegisol in Plastic Container a composite score of 3.0 out of 5, currently based on 1 weighted source (FDA regulatory recall-safety data weighted highest). See our methodology at /how-we-rate.

How much does Plegisol in Plastic Container cost?

Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $0.04 per ml, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins.

Is there a coupon or discount for Plegisol in Plastic Container?

pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Plegisol in Plastic Container. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.

Who makes Plegisol in Plastic Container?

Plegisol in Plastic Container is marketed by Hospira. You can see Hospira's full profile, rating, and other products on pharmaranks.

Is Plegisol in Plastic Container a brand-name or generic drug?

Plegisol in Plastic Container is a brand-name product with the active ingredient Calcium Chloride and Magnesium Chloride and Potassium Chloride and Sodium Chloride.

Is Plegisol in Plastic Container available over the counter?

No. Plegisol in Plastic Container is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.

What forms does Plegisol in Plastic Container come in?

Plegisol in Plastic Container is currently marketed as injectable, per the FDA's National Drug Code Directory.

Is Plegisol in Plastic Container FDA-registered?

Plegisol in Plastic Container is on record with the U.S. FDA under application number NDA018608. You can verify this on its official FDA label.

Has Plegisol in Plastic Container been recalled by the FDA?

Plegisol in Plastic Container has no FDA recalls recorded under its own application in the openFDA enforcement database. Its recall-safety score reflects its manufacturer's overall recall record. This is general reference, not medical advice — check the FDA recall database for the latest alerts.

Is Plegisol in Plastic Container safe?

There's no single safe-or-not verdict. pharmaranks gives Plegisol in Plastic Container a recall-safety score of 60/100, based on its FDA recall history (no recalls under its own FDA application) — not an efficacy or side-effect rating. Review its FDA-label side effects and warnings before use, and always consult a licensed professional.

What are the side effects of Plegisol in Plastic Container?

Plegisol in Plastic Container's side effects are taken directly from its FDA label. From the label: Intraoperative and perioperative potential hazards of open heart surgery include myocardial infarction, electrocardiographic abnormalities, and arrhythmias, including ventricular fibrillation.… Both common and serious reactions are documented in full on this page. This is general reference from the FDA, not medical advice — always consult a professional.