pherazine dm
Pherazine Dm is a combination medicine containing Dextromethorphan Hydrobromide and Promethazine Hydrochloride.
Dextromethorphan Hydrobromide and Promethazine Hydrochloride · by Halsey
Key facts
- Active ingredient
- Dextromethorphan Hydrobromide and Promethazine Hydrochloride
- Form
- Syrup
- Strength
- Dextromethorphan Hydrobromide 15MG/5ML; Promethazine Hydrochloride 6.25MG/5ML
- Type
- Prescription (Rx)
- Brand or generic
- Generic
- Manufacturer
- Halsey
- Half-life
- about 9 to 16 hours (how long it stays in your system)
- What the pharmacy pays
- ~$2.55 for 30 — not your price
- FDA application
- ANDA088913
- Availability
- Discontinued (per FDA)
How long does Dextromethorphan Hydrobromide and Promethazine Hydrochloride stay in your body?
The elimination half-life of dextromethorphan hydrobromide and promethazine hydrochloride is about 9 to 16 hours — the time it takes the body to clear about half of it. As a rule of thumb, a medicine is mostly gone after roughly 4 to 5 half-lives, though this varies from person to person with age and kidney or liver function. Kinetics are linear (no saturable/dose-dependent behavior). The FDA label reports a plasma half-life of 9-16 hours after IV dosing and a mean of 9.8 ± 3.4 hours after IM dosing; the oral tablet label omits a numeric half-life but describes the same disposition. Duration of clinical effect (about 4-6 hours, occasionally up to 12) is shorter than the elimination half-life, so sedation can wear off well before the drug clears. Promethazine is metabolized in the liver to sulfoxides of promethazine and N-desmethylpromethazine (the main urinary metabolites); the label does not characterize these as clinically active or as outlasting the parent. Not a prodrug. Because clearance is hepatic, impaired liver function may prolong the half-life; the label gives no specific age- or kidney-based half-life values.
This is general information, not medical advice. It doesn’t tell you when a drug test would read negative (tests detect substances for different, often longer, windows) or when it’s safe to take another dose — ask your pharmacist or prescriber. Source: Promethazine Hydrochloride Injection, USP — FDA label (DailyMed).
Dosage forms
Syrup
The forms currently marketed in the U.S., per the FDA National Drug Code Directory.
Ways to save
Ask for the generic
Same active ingredient, far cheaper. Is there a generic? →
Request a 90-day supply
Bulk fills usually lower the per-dose price vs monthly refills.
Use copay cards
Manufacturer copay cards & patient-assistance programs — especially for brand drugs.
Compare alternatives
A same-class option may cost less. See alternatives →
Frequently asked questions
- How much does Pherazine Dm cost?
- Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $2.55 for 30, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins.
- Is there a coupon or discount for Pherazine Dm?
- pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Pherazine Dm. To pay less, Pherazine Dm is already a generic — usually the lowest-cost version — so the main levers are comparing cash prices between pharmacies and using a pharmacy discount-card service. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
- Who makes Pherazine Dm?
- Pherazine Dm is marketed by Halsey. You can see Halsey's full profile, rating, and other products on pharmaranks.
- Is Pherazine Dm a brand-name or generic drug?
- Pherazine Dm is a generic medication; its active ingredient is Dextromethorphan Hydrobromide and Promethazine Hydrochloride. Generics contain the same active ingredient as the brand-name original and are usually lower cost.
- Is Pherazine Dm available over the counter?
- No. Pherazine Dm is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
- What forms does Pherazine Dm come in?
- Pherazine Dm is currently marketed as syrup, per the FDA's National Drug Code Directory.
- Is Pherazine Dm FDA-registered?
- Pherazine Dm is on record with the U.S. FDA under application number ANDA088913. You can verify this on its official FDA label.
Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.
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