phenergan vc w/ codeine

How long does Codeine Phosphate and Promethazine Hydrochloride and Phenylephrine Hydrochloride stay in your body?

The elimination half-life of codeine phosphate and promethazine hydrochloride and phenylephrine hydrochloride is about 9 to 16 hours — the time it takes the body to clear about half of it. As a rule of thumb, a medicine is mostly gone after roughly 4 to 5 half-lives, though this varies from person to person with age and kidney or liver function. Kinetics are linear (no saturable/dose-dependent behavior). The FDA label reports a plasma half-life of 9-16 hours after IV dosing and a mean of 9.8 ± 3.4 hours after IM dosing; the oral tablet label omits a numeric half-life but describes the same disposition. Duration of clinical effect (about 4-6 hours, occasionally up to 12) is shorter than the elimination half-life, so sedation can wear off well before the drug clears. Promethazine is metabolized in the liver to sulfoxides of promethazine and N-desmethylpromethazine (the main urinary metabolites); the label does not characterize these as clinically active or as outlasting the parent. Not a prodrug. Because clearance is hepatic, impaired liver function may prolong the half-life; the label gives no specific age- or kidney-based half-life values.

This is general information, not medical advice. It doesn’t tell you when a drug test would read negative (tests detect substances for different, often longer, windows) or when it’s safe to take another dose — ask your pharmacist or prescriber. Source: Promethazine Hydrochloride Injection, USP — FDA label (DailyMed).

Frequently asked questions

How is Phenergan Vc W/ Codeine rated?

pharmaranks gives Phenergan Vc W/ Codeine a composite score of 3.5 out of 5, currently based on 1 weighted source (FDA regulatory recall-safety data weighted highest). See our methodology at /how-we-rate.

How much does Phenergan Vc W/ Codeine cost?

Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $20.54 for 30, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins.

Is there a coupon or discount for Phenergan Vc W/ Codeine?

pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Phenergan Vc W/ Codeine. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.

Who makes Phenergan Vc W/ Codeine?

Phenergan Vc W/ Codeine is marketed by Ani Pharms. You can see Ani Pharms's full profile, rating, and other products on pharmaranks.

Is Phenergan Vc W/ Codeine a brand-name or generic drug?

Phenergan Vc W/ Codeine is a brand-name product with the active ingredient Codeine Phosphate and Promethazine Hydrochloride and Phenylephrine Hydrochloride.

Is Phenergan Vc W/ Codeine available over the counter?

No. Phenergan Vc W/ Codeine is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.

What forms does Phenergan Vc W/ Codeine come in?

Phenergan Vc W/ Codeine is currently marketed as syrup, per the FDA's National Drug Code Directory.

Is Phenergan Vc W/ Codeine FDA-registered?

Phenergan Vc W/ Codeine is on record with the U.S. FDA under application number NDA008306. You can verify this on its official FDA label.

Has Phenergan Vc W/ Codeine been recalled by the FDA?

Phenergan Vc W/ Codeine has no FDA recalls recorded under its own application in the openFDA enforcement database. Its recall-safety score reflects its manufacturer's overall recall record. This is general reference, not medical advice — check the FDA recall database for the latest alerts.

Is Phenergan Vc W/ Codeine safe?

There's no single safe-or-not verdict. pharmaranks gives Phenergan Vc W/ Codeine a recall-safety score of 70/100, based on its FDA recall history (no recalls under its own FDA application) — not an efficacy or side-effect rating. Review its FDA-label side effects and warnings before use, and always consult a licensed professional.