penthrane
Pharmaranks rates Penthrane 3.6/5 for recall safety — an independent score from its FDA recall history and its manufacturer's record. Penthrane (Methoxyflurane) is a medication supplied as a liquid.
Methoxyflurane · by Abbott
Based on 1 source · Recall-safety score from FDA recall history — this product's own recalls and its manufacturer's record. Not an efficacy or quality rating. methodology →
Key facts
- Active ingredient
- Methoxyflurane
- Form
- Liquid
- Strength
- Methoxyflurane 99.9%
- Type
- Prescription (Rx)
- Brand or generic
- Brand-name
- Manufacturer
- Abbott
- FDA application
- NDA013056
- Availability
- Discontinued (per FDA)
Dosage forms
Liquid
The forms currently marketed in the U.S., per the FDA National Drug Code Directory.
Ways to save
Ask for the generic
Same active ingredient, far cheaper. Is there a generic? →
Request a 90-day supply
Bulk fills usually lower the per-dose price vs monthly refills.
Use copay cards
Manufacturer copay cards & patient-assistance programs — especially for brand drugs.
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Frequently asked questions
- How is Penthrane rated?
- pharmaranks gives Penthrane a composite score of 3.6 out of 5, currently based on 1 weighted source (FDA regulatory recall-safety data weighted highest). See our methodology at /how-we-rate.
- Is there a coupon or discount for Penthrane?
- pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Penthrane. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
- Who makes Penthrane?
- Penthrane is marketed by Abbott. You can see Abbott's full profile, rating, and other products on pharmaranks.
- Is Penthrane a brand-name or generic drug?
- Penthrane is a brand-name product with the active ingredient Methoxyflurane.
- Is Penthrane available over the counter?
- No. Penthrane is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
- What forms does Penthrane come in?
- Penthrane is currently marketed as liquid, per the FDA's National Drug Code Directory.
- Is Penthrane FDA-registered?
- Penthrane is on record with the U.S. FDA under application number NDA013056. You can verify this on its official FDA label.
- Has Penthrane been recalled by the FDA?
- Penthrane has no FDA recalls recorded under its own application in the openFDA enforcement database. Its recall-safety score reflects its manufacturer's overall recall record. This is general reference, not medical advice — check the FDA recall database for the latest alerts.
- Is Penthrane safe?
- There's no single safe-or-not verdict. pharmaranks gives Penthrane a recall-safety score of 72/100, based on its FDA recall history (no recalls under its own FDA application) — not an efficacy or side-effect rating. Review its FDA-label side effects and warnings before use, and always consult a licensed professional.
Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.
What people report to the FDA about METHOXYFLURANE
The FDA Adverse Event Reporting System (FAERS) collects reports from patients and clinicians. It holds 65 reports naming METHOXYFLURANE — the active ingredient in Penthrane, and the FDA flagged 100% of those reports as serious. The effects reported most often — leaving out reports about overdose, misuse or the condition being treated, which dominate the raw list for common medicines:
- renal impairment11 reports
- bone marrow failure8 reports
- sepsis8 reports
- vomiting8 reports
- dyspnoea7 reports
- myocardial infarction7 reports
- pain in extremity7 reports
- pneumonia7 reports
Read these as a signal, not a rate. A report does not mean METHOXYFLURANE caused the effect — anyone can file one, and many describe people taking several medicines for several conditions. Crucially there is no denominator: FAERS does not record how many people took the drug, so these counts cannot be turned into “X% of patients” — a bigger number often just means a more widely used or more talked-about drug. Duplicates exist, and publicity drives reporting. For what is actually established, read the FDA label.
Source: openFDA drug/event (FAERS), retrieved September 25, 2026.
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penthrane
72/100