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oxsoralen

Pharmaranks rates Oxsoralen 3.5/5 for recall safety — an independent score from its FDA recall history and its manufacturer's record. Oxsoralen (Methoxsalen) is a photoactivated radical generator used to treat Mycosis Fungoides, Psoriasis, Vitiligo.

Methoxsalen · by Valeant Pharm Intl

70/100Limited · 1 source

Based on 1 source · Recall-safety score from FDA recall history — this product's own recalls and its manufacturer's record. Not an efficacy or quality rating. methodology →

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate
Verified againstopenFDANIH DailyMedRxClass
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Key facts

Active ingredient
Methoxsalen
Form
Topical
Strength
Methoxsalen 1%
Type
Prescription (Rx)
Brand or generic
Brand-name
Manufacturer
Valeant Pharm Intl
Half-life
approximately 2 hours (how long it stays in your system)
FDA application
NDA009048
Availability
Discontinued (per FDA)

How long does Methoxsalen stay in your body?

The elimination half-life of methoxsalen is approximately 2 hours — the time it takes the body to clear about half of it. As a rule of thumb, a medicine is mostly gone after roughly 4 to 5 half-lives, though this varies from person to person with age and kidney or liver function. The oral methoxsalen (PUVA) label reports a single "drug half-life is approximately 2 hours" without separating a distribution and a terminal phase, so 2 hours is the elimination half-life as stated. Detectable methoxsalen blood levels persist up to about 12 hours post-dose. The drug is rapidly metabolized, with roughly 95% excreted as metabolites in the urine within 24 hours; the label does not name any active metabolite that outlasts the parent, so photosensitivity is driven by the parent drug plus UVA exposure. The label does not state how the half-life changes with older age, kidney impairment, or liver impairment. This is a pharmacokinetic half-life, not a drug-test detection window and not dosing guidance.

This is general information, not medical advice. It doesn’t tell you when a drug test would read negative (tests detect substances for different, often longer, windows) or when it’s safe to take another dose — ask your pharmacist or prescriber. Source: Methoxsalen Capsules (oral) — FDA label, DailyMed.

Drug class

May treat (source: NIH RxClass)

Dosage forms

Topical

The forms currently marketed in the U.S., per the FDA National Drug Code Directory.

Ways to save

Ask for the generic

Same active ingredient, far cheaper. Is there a generic? →

Request a 90-day supply

Bulk fills usually lower the per-dose price vs monthly refills.

Use copay cards

Manufacturer copay cards & patient-assistance programs — especially for brand drugs.

Compare alternatives

A same-class option may cost less. See alternatives →

Frequently asked questions

What does Oxsoralen treat?
Oxsoralen (Methoxsalen) may be used to treat mycosis fungoides, psoriasis, vitiligo, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.
How is Oxsoralen rated?
pharmaranks gives Oxsoralen a composite score of 3.5 out of 5, currently based on 1 weighted source (FDA regulatory recall-safety data weighted highest). See our methodology at /how-we-rate.
Is there a coupon or discount for Oxsoralen?
pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Oxsoralen. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
Who makes Oxsoralen?
Oxsoralen is marketed by Valeant Pharm Intl. You can see Valeant Pharm Intl's full profile, rating, and other products on pharmaranks.
Is Oxsoralen a brand-name or generic drug?
Oxsoralen is a brand-name product with the active ingredient Methoxsalen.
Is Oxsoralen available over the counter?
No. Oxsoralen is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
What forms does Oxsoralen come in?
Oxsoralen is currently marketed as topical, per the FDA's National Drug Code Directory.
What class of drug is Oxsoralen?
Oxsoralen is classified as photoactivated radical generator, psoralen, per the FDA's Established Pharmacologic Class.
Is Oxsoralen FDA-registered?
Oxsoralen is on record with the U.S. FDA under application number NDA009048. You can verify this on its official FDA label.
Has Oxsoralen been recalled by the FDA?
Oxsoralen has no FDA recalls recorded under its own application in the openFDA enforcement database. Its recall-safety score reflects its manufacturer's overall recall record. This is general reference, not medical advice — check the FDA recall database for the latest alerts.
Is Oxsoralen safe?
There's no single safe-or-not verdict. pharmaranks gives Oxsoralen a recall-safety score of 70/100, based on its FDA recall history (no recalls under its own FDA application) — not an efficacy or side-effect rating. Review its FDA-label side effects and warnings before use, and always consult a licensed professional.

Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.

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