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orsythia

Orsythia is a combination medicine containing Ethinyl Estradiol and Levonorgestrel.

Ethinyl Estradiol and Levonorgestrel · by Ph Health

Generic of Loseasonique

Not yet rated· sourced from the FDA label
Rated against independent regulatory sources·Last updated June 7, 2026·How we rate
Verified againstopenFDANIH DailyMedRxClass

Key facts

Active ingredient
Ethinyl Estradiol and Levonorgestrel
Form
Tablet
Strength
Ethinyl Estradiol 0.02MG; Levonorgestrel 0.1MG
Type
Prescription (Rx)
Brand or generic
Generic
Manufacturer
Ph Health
Half-life
about 36 hours (36 ± 13 hours at steady state) (how long it stays in your system)
FDA application
ANDA077099
Availability
Discontinued (per FDA)

How long does Ethinyl Estradiol and Levonorgestrel stay in your body?

The elimination half-life of ethinyl estradiol and levonorgestrel is about 36 hours (36 ± 13 hours at steady state) — the time it takes the body to clear about half of it. As a rule of thumb, a medicine is mostly gone after roughly 4 to 5 half-lives, though this varies from person to person with age and kidney or liver function. This is the terminal elimination half-life stated directly for levonorgestrel; the label reports no active metabolite that outlasts the parent, and levonorgestrel is not a prodrug. The number comes from a levonorgestrel/ethinyl estradiol combination oral-contraceptive label (Aviane), where it is attributed specifically to the levonorgestrel component; the single-ingredient OTC emergency-contraceptive labels do not state a half-life. On populations: the label says no formal studies evaluated hepatic or renal impairment, but cautions that steroid hormones may be poorly metabolized in patients with impaired liver function; it notes no apparent pharmacokinetic differences across races, and states nothing about older adults.

This is general information, not medical advice. It doesn’t tell you when a drug test would read negative (tests detect substances for different, often longer, windows) or when it’s safe to take another dose — ask your pharmacist or prescriber. Source: Aviane (levonorgestrel and ethinyl estradiol) label — DailyMed, Clinical Pharmacology / Pharmacokinetics.

Dosage forms

Tablet

The forms currently marketed in the U.S., per the FDA National Drug Code Directory.

Ways to save

Ask for the generic

Same active ingredient, far cheaper. Is there a generic? →

Request a 90-day supply

Bulk fills usually lower the per-dose price vs monthly refills.

Use copay cards

Manufacturer copay cards & patient-assistance programs — especially for brand drugs.

Compare alternatives

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Frequently asked questions

Is there a coupon or discount for Orsythia?
pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Orsythia. To pay less, Orsythia is already a generic — usually the lowest-cost version — so the main levers are comparing cash prices between pharmacies and using a pharmacy discount-card service. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
Who makes Orsythia?
Orsythia is marketed by Ph Health. You can see Ph Health's full profile, rating, and other products on pharmaranks.
Is Orsythia a brand-name or generic drug?
Orsythia is a generic medication; its active ingredient is Ethinyl Estradiol and Levonorgestrel. Generics contain the same active ingredient as the brand-name original and are usually lower cost.
Is Orsythia available over the counter?
No. Orsythia is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
What forms does Orsythia come in?
Orsythia is currently marketed as tablet, per the FDA's National Drug Code Directory.
Is Orsythia FDA-registered?
Orsythia is on record with the U.S. FDA under application number ANDA077099. You can verify this on its official FDA label.

Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.

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