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oreticyl 25

Pharmaranks rates Oreticyl 25 3.6/5 for recall safety — an independent score from its FDA recall history and its manufacturer's record. Oreticyl 25 is a combination medicine containing Deserpidine and Hydrochlorothiazide.

Deserpidine and Hydrochlorothiazide · by Abbvie

72/100Limited · 1 source

Based on 1 source · Recall-safety score from FDA recall history — this product's own recalls and its manufacturer's record. Not an efficacy or quality rating. methodology →

Rated against independent regulatory sources·Last updated August 19, 2026·How we rate
Verified againstopenFDANIH DailyMedRxClass

Key facts

Active ingredient
Deserpidine and Hydrochlorothiazide
Form
Tablet
Strength
Deserpidine 0.125MG; Hydrochlorothiazide 25MG
Type
Prescription (Rx)
Brand or generic
Brand-name
Manufacturer
Abbvie
Half-life
about 6 to 15 hours (the label reports a range, not a single number) (how long it stays in your system)
FDA application
NDA012148
Availability
Discontinued (per FDA)

How long does Deserpidine and Hydrochlorothiazide stay in your body?

The elimination half-life of deserpidine and hydrochlorothiazide is about 6 to 15 hours (the label reports a range, not a single number) — the time it takes the body to clear about half of it. As a rule of thumb, a medicine is mostly gone after roughly 4 to 5 half-lives, though this varies from person to person with age and kidney or liver function. This is the plasma ELIMINATION half-life. Plasma levels fall bi-exponentially: other FDA labels for hydrochlorothiazide combination products describe a distribution phase of roughly 2 hours before the ~10-hour (6-15 h) elimination phase — the elimination figure is the one given here. Hydrochlorothiazide is NOT a prodrug and is NOT metabolized, so there is no active metabolite that outlasts the parent; more than 95% of the absorbed dose is excreted unchanged in urine. Kidney impairment: the label states plainly that in patients with renal disease plasma concentrations are increased and the elimination half-life is PROLONGED — it does not quantify by how much. The label does not state a different half-life for older adults or for liver impairment, so no number should be assumed for those groups. Absorption (not elimination) is reduced in congestive heart failure. This is a pharmacokinetic figure about how long the drug stays in plasma; it is not a drug-test detection window and not dosing guidance.

This is general information, not medical advice. It doesn’t tell you when a drug test would read negative (tests detect substances for different, often longer, windows) or when it’s safe to take another dose — ask your pharmacist or prescriber. Source: DailyMed — HYDROCHLOROTHIAZIDE capsule, Clinical Pharmacology (Pharmacokinetics and Metabolism).

Dosage forms

Tablet

The forms currently marketed in the U.S., per the FDA National Drug Code Directory.

Ways to save

Ask for the generic

Same active ingredient, far cheaper. Is there a generic? →

Request a 90-day supply

Bulk fills usually lower the per-dose price vs monthly refills.

Use copay cards

Manufacturer copay cards & patient-assistance programs — especially for brand drugs.

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Frequently asked questions

How is Oreticyl 25 rated?
pharmaranks gives Oreticyl 25 a composite score of 3.6 out of 5, currently based on 1 weighted source (FDA regulatory recall-safety data weighted highest). See our methodology at /how-we-rate.
Is there a coupon or discount for Oreticyl 25?
pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Oreticyl 25. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
Who makes Oreticyl 25?
Oreticyl 25 is marketed by Abbvie. You can see Abbvie's full profile, rating, and other products on pharmaranks.
Is Oreticyl 25 a brand-name or generic drug?
Oreticyl 25 is a brand-name product with the active ingredient Deserpidine and Hydrochlorothiazide.
Is Oreticyl 25 available over the counter?
No. Oreticyl 25 is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
What forms does Oreticyl 25 come in?
Oreticyl 25 is currently marketed as tablet, per the FDA's National Drug Code Directory.
Is Oreticyl 25 FDA-registered?
Oreticyl 25 is on record with the U.S. FDA under application number NDA012148. You can verify this on its official FDA label.
Has Oreticyl 25 been recalled by the FDA?
Oreticyl 25 has no FDA recalls recorded under its own application in the openFDA enforcement database. Its recall-safety score reflects its manufacturer's overall recall record. This is general reference, not medical advice — check the FDA recall database for the latest alerts.
Is Oreticyl 25 safe?
There's no single safe-or-not verdict. pharmaranks gives Oreticyl 25 a recall-safety score of 72/100, based on its FDA recall history (no recalls under its own FDA application) — not an efficacy or side-effect rating. Review its FDA-label side effects and warnings before use, and always consult a licensed professional.

Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.

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oreticyl 25

72/100