ophthocort

How long does Chloramphenicol and Hydrocortisone Acetate and Polymyxin B Sulfate stay in your body?

The elimination half-life of chloramphenicol and hydrocortisone acetate and polymyxin b sulfate is about 1.5 hours — the time it takes the body to clear about half of it. As a rule of thumb, a medicine is mostly gone after roughly 4 to 5 half-lives, though this varies from person to person with age and kidney or liver function. This is the plasma (terminal) elimination half-life; the FDA label states "The terminal half-life of hydrocortisone is about 1.5 hours following intravenous and oral dosing of hydrocortisone tablets" in healthy adults, so roughly 90% of a dose clears within about 8 hours and nearly all within ~12 hours. Hydrocortisone is not a prodrug, but its half-life measures how fast the drug leaves the blood, not how long its effects last: as a short-acting glucocorticoid its biological (tissue) effect on the body persists well beyond blood clearance, and this short plasma half-life is why oral replacement is usually dosed 2-3 times a day. Because hydrocortisone is metabolized in the liver, significant liver impairment can slow clearance; the label does not give a specific half-life adjustment for age, kidney, or liver function. Half-life is not the same as a drug-test detection window.

This is general information, not medical advice. It doesn’t tell you when a drug test would read negative (tests detect substances for different, often longer, windows) or when it’s safe to take another dose — ask your pharmacist or prescriber. Source: ALKINDI SPRINKLE (hydrocortisone) oral granules — FDA prescribing information, DailyMed.

Frequently asked questions

Is there a coupon or discount for Ophthocort?

pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Ophthocort. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.

Who makes Ophthocort?

Ophthocort is marketed by Parkedale. You can see Parkedale's full profile, rating, and other products on pharmaranks.

Is Ophthocort a brand-name or generic drug?

Ophthocort is a brand-name product with the active ingredient Chloramphenicol and Hydrocortisone Acetate and Polymyxin B Sulfate.

Is Ophthocort available over the counter?

No. Ophthocort is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.

What forms does Ophthocort come in?

Ophthocort is currently marketed as topical, per the FDA's National Drug Code Directory.

Is Ophthocort FDA-registered?

Ophthocort is on record with the U.S. FDA under application number NDA050201. You can verify this on its official FDA label.