ophthaine
Ophthaine (Proparacaine Hydrochloride) is a medication supplied as a solution/drops.
Proparacaine Hydrochloride · by Apothecon
Key facts
- Active ingredient
- Proparacaine Hydrochloride
- Form
- Drops
- Strength
- Proparacaine Hydrochloride 0.5% **Federal Register Determination That Product was not Discontinued or Withdrawn for Safety or Effectiveness reasons**
- Type
- Prescription (Rx)
- Brand or generic
- Brand-name
- Manufacturer
- Apothecon
- What the pharmacy pays
- ~$1.59 per ml — not your price
- FDA application
- NDA008883
- Availability
- Discontinued (per FDA)
Dosage forms
Drops
The forms currently marketed in the U.S., per the FDA National Drug Code Directory.
Ways to save
Ask for the generic
Same active ingredient, far cheaper. Is there a generic? →
Request a 90-day supply
Bulk fills usually lower the per-dose price vs monthly refills.
Use copay cards
Manufacturer copay cards & patient-assistance programs — especially for brand drugs.
Compare alternatives
A same-class option may cost less. See alternatives →
Frequently asked questions
- How much does Ophthaine cost?
- Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $1.59 per ml, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins. Pharmacies pay less for a same-class option, Tolak — about $0.61 on the same basis.
- Is there a coupon or discount for Ophthaine?
- pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Ophthaine. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
- Who makes Ophthaine?
- Ophthaine is marketed by Apothecon. You can see Apothecon's full profile, rating, and other products on pharmaranks.
- Is Ophthaine a brand-name or generic drug?
- Ophthaine is a brand-name product with the active ingredient Proparacaine Hydrochloride.
- Is Ophthaine available over the counter?
- No. Ophthaine is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
- What forms does Ophthaine come in?
- Ophthaine is currently marketed as drops, per the FDA's National Drug Code Directory.
- Is Ophthaine FDA-registered?
- Ophthaine is on record with the U.S. FDA under application number NDA008883. You can verify this on its official FDA label.
Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.
What people report to the FDA about PROPARACAINE HYDROCHLORIDE
The FDA Adverse Event Reporting System (FAERS) collects reports from patients and clinicians. It holds 258 reports naming PROPARACAINE HYDROCHLORIDE — the active ingredient in Ophthaine, and the FDA flagged 82% of those reports as serious. The effects reported most often — leaving out reports about overdose, misuse or the condition being treated, which dominate the raw list for common medicines:
- eye pain19 reports
- vomiting19 reports
- vision blurred18 reports
- abdominal distension17 reports
- apnoea16 reports
- feeding intolerance16 reports
- gastric residual increased16 reports
- eye irritation13 reports
Read these as a signal, not a rate. A report does not mean PROPARACAINE HYDROCHLORIDE caused the effect — anyone can file one, and many describe people taking several medicines for several conditions. Crucially there is no denominator: FAERS does not record how many people took the drug, so these counts cannot be turned into “X% of patients” — a bigger number often just means a more widely used or more talked-about drug. Duplicates exist, and publicity drives reporting. For what is actually established, read the FDA label.
Source: openFDA drug/event (FAERS), retrieved September 26, 2026.
Reviews
No reviews yet. Be the first to write one.
People also viewed
benzamycin
Benzoyl Peroxide and Erythromycin
colazal
Balsalazide Disodium
cuprimine
Penicillamine
mysoline
Primidone
retin-a
Tretinoin
tolak
Fluorouracil
Compare Ophthaine head-to-head
Browse medications A–Z
Research products from A to Z, compare independent ratings, and find alternatives.
ophthaine
New