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naftifine hydrochloride

Naftifine Hydrochloride is a medication used to treat Tinea Pedis.

Generic · by Sun Pharma Canada

Generic of Naftin

Not yet rated· sourced from the FDA label
Rated against independent regulatory sources·Last updated June 7, 2026·How we rate
Verified againstopenFDANIH DailyMedRxClass

Key facts

Active ingredient
Naftifine Hydrochloride
Form
Topical
Strength
Naftifine Hydrochloride 1%
Type
Prescription (Rx)
Brand or generic
Generic
May treat
tinea pedis
Manufacturer
Sun Pharma Canada
What the pharmacy pays
~$2.23 per gm — not your price
FDA application
ANDA205975

What is Naftifine Hydrochloride?

From the FDA label:Naftifine Hydrochloride Cream USP, 1% contains the synthetic, broad-spectrum, antifungal agent naftifine hydrochloride. Naftifine Hydrochloride Cream USP, 1% is for topical use only. CHEMICAL NAME: (E)-N-Cinnamyl-N-methyl-1-naphthalenemethylamine hydrochloride. Naftifine hydrochloride has an empirical formula of C 21 H 21 N∙HCl and a molecular weight of 323.86. Structural Formula naftifine hydrochloride Contains Active Ingredient Naftifine hydrochloride 1% Inactive Ingredients benzyl alcohol, cetyl alcohol, cetyl esters wax, isopropyl myristate, polysorbate 60, purified water, sodium hydroxide, sorbitan monostearate, and stearyl alcohol. Hydrochloric acid may be added to adjust pH. Chemical Structure

How to use

A sufficient quantity of Naftifine Hydrochloride Cream USP, 1% should be gently massaged into the affected and surrounding skin areas once a day. The hands should be washed after application. If no clinical improvement is seen after four weeks of treatment with Naftifine Hydrochloride Cream USP, 1%, the patient should be re-evaluated.

Side effects

During clinical trials with Naftifine Hydrochloride Cream USP, 1%, the incidence of adverse reactions was as follows: burning/stinging (6%), dryness (3%), erythema (2%), itching (2%), local irritation (2%).

Warnings

Important safety information

Naftifine Hydrochloride Cream USP, 1% is for topical use only and not for ophthalmic use.

Who should not take Naftifine Hydrochloride

Naftifine Hydrochloride Cream USP, 1% is contraindicated in individuals who have shown hypersensitivity to any of its components.

May treat (source: NIH RxClass)

Dosage forms

Topical

The forms currently marketed in the U.S., per the FDA National Drug Code Directory.

Ways to save

Ask for the generic

Same active ingredient, far cheaper. Is there a generic? →

Request a 90-day supply

Bulk fills usually lower the per-dose price vs monthly refills.

Use copay cards

Manufacturer copay cards & patient-assistance programs — especially for brand drugs.

Compare alternatives

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Frequently asked questions

What does Naftifine Hydrochloride treat?
Naftifine Hydrochloride (Naftifine Hydrochloride) may be used to treat tinea pedis, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.
How much does Naftifine Hydrochloride cost?
Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $2.23 per gm, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins.
Is there a coupon or discount for Naftifine Hydrochloride?
pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Naftifine Hydrochloride. To pay less, Naftifine Hydrochloride is already a generic — usually the lowest-cost version — so the main levers are comparing cash prices between pharmacies and using a pharmacy discount-card service. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
Who makes Naftifine Hydrochloride?
Naftifine Hydrochloride is marketed by Sun Pharma Canada. You can see Sun Pharma Canada's full profile, rating, and other products on pharmaranks.
Is Naftifine Hydrochloride a brand-name or generic drug?
Naftifine Hydrochloride is a generic medication; its active ingredient is Naftifine Hydrochloride. Generics contain the same active ingredient as the brand-name original and are usually lower cost.
Is Naftifine Hydrochloride available over the counter?
No. Naftifine Hydrochloride is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
What forms does Naftifine Hydrochloride come in?
Naftifine Hydrochloride is currently marketed as topical, per the FDA's National Drug Code Directory.
Is Naftifine Hydrochloride FDA-registered?
Naftifine Hydrochloride is on record with the U.S. FDA under application number ANDA205975. You can verify this on its official FDA label.
Is Naftifine Hydrochloride safe?
There's no single safe-or-not verdict, and we don't yet have a composite recall-safety score for Naftifine Hydrochloride. Review its FDA-label side effects and warnings below, and always consult a licensed professional.
What are the side effects of Naftifine Hydrochloride?
Naftifine Hydrochloride's side effects are taken directly from its FDA label. From the label: During clinical trials with Naftifine Hydrochloride Cream USP, 1%, the incidence of adverse reactions was as follows: burning/stinging (6%), dryness (3%), erythema (2%), itching (2%), local irritation (2%). Both common and serious reactions are documented in full on this page. This is general reference from the FDA, not medical advice — always consult a professional.

Clinical content sourced from the FDA label via openFDA (U.S. FDA). View the FDA label on DailyMed → Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.

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