
mpi indium dtpa in 111
Mpi Indium Dtpa in 111 (Indium in-111 Pentetate Disodium) is a medication supplied as a solution.
Indium in-111 Pentetate Disodium · by Ge Healthcare
Key facts
- Active ingredient
- Indium in-111 Pentetate Disodium
- Form
- Solution
- Strength
- Indium IN-111 Pentetate Disodium 1mCi/ML
- Type
- Prescription (Rx)
- Brand or generic
- Brand-name
- Manufacturer
- Ge Healthcare
- FDA application
- NDA017707
What is Mpi Indium Dtpa in 111?
From the FDA label:GE Healthcare (Medi-Physics, Inc.) Indium DTPA In 111 is a diagnostic drug for intrathecal use. It is available as a sterile, pyrogen-free, isotonic, aqueous solution, buffered to pH 7 to 8. At calibration time, each milliliter contains 37 MBq, 1 mCi of Pentetate Indium Disodium In 111 (no-carrier-added), 20 to 50 µ g of pentetic acid, and sodium bicarbonate for pH adjustment. The drug is to be discarded after single use. Radionuclidic purity at calibration time is at least 99.88% with less than 0.06% Indium In 114m and 0.06% Zinc Zn 65. The concentration of each radionuclidic contaminant changes with time. Graph 1 shows maximum concentration of each radionuclidic impurity as a function of time. Graph 1 - Radionuclidic Impurities The chemical names are 1. Indate(2-)- 111 In -[ N,N -bis[2-[bis-(carboxymethyl)amino]ethyl]glycinato(5-)]-disodium; and 2. Disodium [ N,N -bis[2-(carboxymethyl)amino]glycinato(5-)]-indate (2-) 111 In. Molecular formula: C 14 H 18 O 10 N 3 111 In Na 2 Molecular weight: 545.29 Structural formula: PHYSICAL CHARACTERISTICS Indium 111 decays by electron capture with a physical half-life of 67.9 hours. The energies of the photons that are useful for detection and imaging studies are listed in Table 1. Table 1. Principal Radiation Emission Data Kocher, David C.,"Radioactive Decay Data Tables,"DOE/TIC-11026, 115, (1981). Radiation Mean %/Disintegration Mean…
How to use
Extreme care must be exercised to assure aseptic conditions in intrathecal injections. The maximum recommended intrathecal dose in the average patient (70 kg) is 18.5 MBq, 500 µ Ci. The patient dose should be measured by a suitable radioactivity calibration system immediately prior to administration. Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration whenever solution and container permit.
Side effects
Aseptic meningitis and pyrogenic reactions have been rarely (less than 0.4%) observed following cisternography with Pentetate lndium Disodium In 111. One death has been reported to have occurred within 20 minutes following the administration of Pentetate Indium Disodium In 111 and appears to be drug related. In addition, two cases of septic meningitis have also been reported. There have also been reports of skin reactions and vomiting following administration of Pentetate lndium Disodium In 111. Relationship of the drug to these latter occurrences has not been established.
Warnings
Important safety information
The contents of the vial are radioactive. Adequate shielding of the preparation must be maintained at all times. Since the drug is excreted by the kidneys, caution should be exercised in patients with severely impaired renal function.
Who should not take Mpi Indium Dtpa in 111
None known.
Dosage forms
Solution
The forms currently marketed in the U.S., per the FDA National Drug Code Directory.
Ways to save
Ask for the generic
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Use copay cards
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Frequently asked questions
- Is there a coupon or discount for Mpi Indium Dtpa in 111?
- pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Mpi Indium Dtpa in 111. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
- Who makes Mpi Indium Dtpa in 111?
- Mpi Indium Dtpa in 111 is marketed by Ge Healthcare. You can see Ge Healthcare's full profile, rating, and other products on pharmaranks.
- Is Mpi Indium Dtpa in 111 a brand-name or generic drug?
- Mpi Indium Dtpa in 111 is a brand-name product with the active ingredient Indium in-111 Pentetate Disodium.
- Is Mpi Indium Dtpa in 111 available over the counter?
- No. Mpi Indium Dtpa in 111 is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
- What forms does Mpi Indium Dtpa in 111 come in?
- Mpi Indium Dtpa in 111 is currently marketed as solution, per the FDA's National Drug Code Directory.
- Is Mpi Indium Dtpa in 111 FDA-registered?
- Mpi Indium Dtpa in 111 is on record with the U.S. FDA under application number NDA017707. You can verify this on its official FDA label.
- Is Mpi Indium Dtpa in 111 safe?
- There's no single safe-or-not verdict, and we don't yet have a composite recall-safety score for Mpi Indium Dtpa in 111. Review its FDA-label side effects and warnings below, and always consult a licensed professional.
- What are the side effects of Mpi Indium Dtpa in 111?
- Mpi Indium Dtpa in 111's side effects are taken directly from its FDA label. From the label: Aseptic meningitis and pyrogenic reactions have been rarely (less than 0.4%) observed following cisternography with Pentetate lndium Disodium In 111. One death has been reported to have occurred within 20 minutes following the administration of Pentetate Indium Disodium In 111 and appears to be drug… Both common and serious reactions are documented in full on this page. This is general reference from the FDA, not medical advice — always consult a professional.
Clinical content sourced from the FDA label via openFDA (U.S. FDA). View the FDA label on DailyMed → Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.
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