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metozolv odt

Metozolv ODT (Metoclopramide Hydrochloride) is a dopamine-2 receptor antagonist used to treat Gastroesophageal Reflux, Gastroparesis, Postoperative Nausea and Vomiting.

Metoclopramide Hydrochloride · by Salix

Available as a generic: Clopra-"Yellow"

Not yet rated· sourced from the FDA label
Rated against independent regulatory sources·Last updated June 7, 2026·How we rate
Verified againstopenFDANIH DailyMedRxClass
~$1.34 /30
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Key facts

Form
Tablet, orally disintegrating
Strength
Metoclopramide Hydrochloride EQ 10MG Base **Federal Register Determination That Product was not Discontinued or Withdrawn for Safety or Effectiveness reasons** · Metoclopramide Hydrochloride EQ 5MG Base **Federal Register Determination That Product was not Discontinued or Withdrawn for Safety or Effectiveness reasons**
Type
Prescription (Rx)
Brand or generic
Brand-name
Manufacturer
Salix
Half-life
about 5 to 6 hours (how long it stays in your system)
What the pharmacy pays
~$1.34 for 30 — not your price
FDA application
NDA022246
Availability
Discontinued (per FDA)

How long does Metoclopramide Hydrochloride stay in your body?

The elimination half-life of metoclopramide hydrochloride is about 5 to 6 hours — the time it takes the body to clear about half of it. As a rule of thumb, a medicine is mostly gone after roughly 4 to 5 half-lives, though this varies from person to person with age and kidney or liver function. This is the average elimination (terminal) half-life in adults with normal renal function; the label gives it as a 5-to-6-hour range and reports no separate distribution-phase figure. Metoclopramide is not a prodrug, and the FDA label does not describe an active metabolite that outlasts the parent — about half of the drug recovered in urine is excreted as free or conjugated (inactive) metoclopramide. Kidney impairment is the population the label singles out: as creatinine clearance falls, plasma, renal and non-renal clearance all fall and the elimination half-life lengthens, so the drug accumulates unless the maintenance dose is reduced. The label does not state a separate adult half-life for older adults or for liver impairment. It does note that in newborns the half-life is much longer (23.1 hours after a first dose in a 3.5-week-old infant) because of immature liver and kidney function, while in older children it is roughly 4 to 4.5 hours. Half-life describes how fast the drug leaves the blood — it is not a drug-test detection window (metabolites are detectable far longer) and not dosing guidance.

This is general information, not medical advice. It doesn’t tell you when a drug test would read negative (tests detect substances for different, often longer, windows) or when it’s safe to take another dose — ask your pharmacist or prescriber. Source: Metoclopramide Oral Solution — FDA label, Clinical Pharmacology / Pharmacokinetics (DailyMed SPL).

Drug class

May treat (source: NIH RxClass)

Dosage forms

Tablet, orally disintegrating

The forms currently marketed in the U.S., per the FDA National Drug Code Directory.

Ways to save

Ask for the generic

Same active ingredient, far cheaper. Is there a generic? →

Request a 90-day supply

Bulk fills usually lower the per-dose price vs monthly refills.

Use copay cards

Manufacturer copay cards & patient-assistance programs — especially for brand drugs.

Compare alternatives

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Frequently asked questions

What does Metozolv ODT treat?
Metozolv ODT (Metoclopramide Hydrochloride) may be used to treat gastroesophageal reflux, gastroparesis, postoperative nausea and vomiting, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.
How much does Metozolv ODT cost?
Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $1.34 for 30, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins.
Is there a coupon or discount for Metozolv ODT?
pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Metozolv ODT. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
Who makes Metozolv ODT?
Metozolv ODT is marketed by Salix. You can see Salix's full profile, rating, and other products on pharmaranks.
Is Metozolv ODT a brand-name or generic drug?
Metozolv ODT is a brand-name product with the active ingredient Metoclopramide Hydrochloride. Lower-cost generic equivalents containing Metoclopramide Hydrochloride are available — ask your pharmacist.
Is Metozolv ODT available over the counter?
No. Metozolv ODT is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
What forms does Metozolv ODT come in?
Metozolv ODT is currently marketed as tablet, orally disintegrating, per the FDA's National Drug Code Directory.
What class of drug is Metozolv ODT?
Metozolv ODT is classified as dopamine-2 receptor antagonist, per the FDA's Established Pharmacologic Class.
Is Metozolv ODT FDA-registered?
Metozolv ODT is on record with the U.S. FDA under application number NDA022246. You can verify this on its official FDA label.

Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.

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