Key facts
- Active ingredient
- Aspirin and Methocarbamol
- Form
- Tablet
- Strength
- Aspirin 325MG; Methocarbamol 400MG
- Type
- Prescription (Rx)
- Brand or generic
- Generic
- Manufacturer
- Stevens J
- Half-life
- about 1 to 2 hours (how long it stays in your system)
- What the pharmacy pays
- ~$0.78 for 30 — not your price
- FDA application
- ANDA081145
- Availability
- Discontinued (per FDA)
How long does Aspirin and Methocarbamol stay in your body?
The elimination half-life of aspirin and methocarbamol is about 1 to 2 hours — the time it takes the body to clear about half of it. As a rule of thumb, a medicine is mostly gone after roughly 4 to 5 half-lives, though this varies from person to person with age and kidney or liver function. The FDA label reports a mean plasma elimination half-life of 1 to 2 hours in healthy volunteers (about 1.1 hours in a younger group). It names no active metabolite: methocarbamol is cleared by dealkylation, hydroxylation and likely conjugation, and essentially all metabolites leave in the urine, with the label describing no lingering active one. Older adults clear it only slightly more slowly (mean 1.5 hours at a mean age of 69, vs 1.1 hours in a younger group). Kidney impairment barely changes the half-life — in 8 hemodialysis patients it was 1.2 hours vs 1.1 hours in normal subjects — even though total clearance fell about 40%. Liver disease matters most: in 8 patients with alcohol-related cirrhosis, total clearance dropped roughly 70% and the mean half-life rose to about 3.4 hours. Protein binding is 46-50% normally and drops to roughly 40-45% in cirrhosis and 41-43% in older adults. These figures come from immediate-release oral tablets and the IM/IV injection; the label covers no extended-release methocarbamol form.
This is general information, not medical advice. It doesn’t tell you when a drug test would read negative (tests detect substances for different, often longer, windows) or when it’s safe to take another dose — ask your pharmacist or prescriber. Source: Methocarbamol Tablets USP — FDA label, Clinical Pharmacology (Pharmacokinetics), DailyMed.
Dosage forms
Tablet
The forms currently marketed in the U.S., per the FDA National Drug Code Directory.
Ways to save
Ask for the generic
Same active ingredient, far cheaper. Is there a generic? →
Request a 90-day supply
Bulk fills usually lower the per-dose price vs monthly refills.
Use copay cards
Manufacturer copay cards & patient-assistance programs — especially for brand drugs.
Compare alternatives
A same-class option may cost less. See alternatives →
Frequently asked questions
- How much does Methocarbamol and Aspirin cost?
- Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $0.78 for 30, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins.
- Is there a coupon or discount for Methocarbamol and Aspirin?
- pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Methocarbamol and Aspirin. To pay less, Methocarbamol and Aspirin is already a generic — usually the lowest-cost version — so the main levers are comparing cash prices between pharmacies and using a pharmacy discount-card service. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
- Who makes Methocarbamol and Aspirin?
- Methocarbamol and Aspirin is marketed by Stevens J. You can see Stevens J's full profile, rating, and other products on pharmaranks.
- Is Methocarbamol and Aspirin a brand-name or generic drug?
- Methocarbamol and Aspirin is a generic medication; its active ingredient is Aspirin and Methocarbamol. Generics contain the same active ingredient as the brand-name original and are usually lower cost.
- Is Methocarbamol and Aspirin available over the counter?
- No. Methocarbamol and Aspirin is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
- What forms does Methocarbamol and Aspirin come in?
- Methocarbamol and Aspirin is currently marketed as tablet, per the FDA's National Drug Code Directory.
- Is Methocarbamol and Aspirin FDA-registered?
- Methocarbamol and Aspirin is on record with the U.S. FDA under application number ANDA081145. You can verify this on its official FDA label.
Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.
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