losartan potassium and hydrochlorothiazide

How long does Hydrochlorothiazide and Losartan Potassium stay in your body?

The elimination half-life of hydrochlorothiazide and losartan potassium is about 6 to 15 hours (the label reports a range, not a single number) — the time it takes the body to clear about half of it. As a rule of thumb, a medicine is mostly gone after roughly 4 to 5 half-lives, though this varies from person to person with age and kidney or liver function. This is the plasma ELIMINATION half-life. Plasma levels fall bi-exponentially: other FDA labels for hydrochlorothiazide combination products describe a distribution phase of roughly 2 hours before the ~10-hour (6-15 h) elimination phase — the elimination figure is the one given here. Hydrochlorothiazide is NOT a prodrug and is NOT metabolized, so there is no active metabolite that outlasts the parent; more than 95% of the absorbed dose is excreted unchanged in urine. Kidney impairment: the label states plainly that in patients with renal disease plasma concentrations are increased and the elimination half-life is PROLONGED — it does not quantify by how much. The label does not state a different half-life for older adults or for liver impairment, so no number should be assumed for those groups. Absorption (not elimination) is reduced in congestive heart failure. This is a pharmacokinetic figure about how long the drug stays in plasma; it is not a drug-test detection window and not dosing guidance.

This is general information, not medical advice. It doesn’t tell you when a drug test would read negative (tests detect substances for different, often longer, windows) or when it’s safe to take another dose — ask your pharmacist or prescriber. Source: DailyMed — HYDROCHLOROTHIAZIDE capsule, Clinical Pharmacology (Pharmacokinetics and Metabolism).

Frequently asked questions

How much does Losartan Potassium and Hydrochlorothiazide cost?

Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $0.91 for 30, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins.

Is there a coupon or discount for Losartan Potassium and Hydrochlorothiazide?

pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Losartan Potassium and Hydrochlorothiazide. To pay less, Losartan Potassium and Hydrochlorothiazide is already a generic — usually the lowest-cost version — so the main levers are comparing cash prices between pharmacies and using a pharmacy discount-card service. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.

Who makes Losartan Potassium and Hydrochlorothiazide?

Losartan Potassium and Hydrochlorothiazide is marketed by Ipca Labs Ltd. You can see Ipca Labs Ltd's full profile, rating, and other products on pharmaranks.

Is Losartan Potassium and Hydrochlorothiazide a brand-name or generic drug?

Losartan Potassium and Hydrochlorothiazide is a generic medication; its active ingredient is Hydrochlorothiazide and Losartan Potassium. Generics contain the same active ingredient as the brand-name original and are usually lower cost.

Is Losartan Potassium and Hydrochlorothiazide available over the counter?

No. Losartan Potassium and Hydrochlorothiazide is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.

What forms does Losartan Potassium and Hydrochlorothiazide come in?

Losartan Potassium and Hydrochlorothiazide is currently marketed as tablet, per the FDA's National Drug Code Directory.

Is Losartan Potassium and Hydrochlorothiazide FDA-registered?

Losartan Potassium and Hydrochlorothiazide is on record with the U.S. FDA under application number ANDA201682. You can verify this on its official FDA label.