loestrin 24 fe

How long does Ethinyl Estradiol and Norethindrone Acetate stay in your body?

The elimination half-life of ethinyl estradiol and norethindrone acetate is about 8 hours — the time it takes the body to clear about half of it. As a rule of thumb, a medicine is mostly gone after roughly 4 to 5 half-lives, though this varies from person to person with age and kidney or liver function. This is the terminal (elimination) half-life, not a distribution phase: the label states "the mean terminal elimination half-life of norethindrone following single dose administration ... is approximately 8 hours," and its single-dose PK table gives t½ = 7.7 ± 0.5 hours (12 healthy women, 0.35 mg, fasting). Norethindrone itself is the active drug, and the label names no active metabolite that outlasts it — it is extensively reduced and then sulfate/glucuronide conjugated, with less than 5% excreted unchanged. Related point for anyone reading a different label: norethindrone ACETATE is a prodrug that is rapidly converted to norethindrone, so norethindrone is the active moiety in those products too. This label does not characterize how the half-life changes in older adults or in kidney or liver impairment — no such pharmacokinetic data is given, so no number can be quoted for those groups (the label does contraindicate use in women with significant liver disease, but that is a safety statement, not a half-life adjustment).

This is general information, not medical advice. It doesn’t tell you when a drug test would read negative (tests detect substances for different, often longer, windows) or when it’s safe to take another dose — ask your pharmacist or prescriber. Source: CAMILA (norethindrone) 0.35 mg tablets — DailyMed label, Clinical Pharmacology / Pharmacokinetics.

Frequently asked questions

Is there a coupon or discount for Loestrin 24 Fe?

pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Loestrin 24 Fe. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.

Who makes Loestrin 24 Fe?

Loestrin 24 Fe is marketed by Teva Branded Pharm. You can see Teva Branded Pharm's full profile, rating, and other products on pharmaranks.

Is Loestrin 24 Fe a brand-name or generic drug?

Loestrin 24 Fe is a brand-name product with the active ingredient Ethinyl Estradiol and Norethindrone Acetate. Lower-cost generic equivalents containing Ethinyl Estradiol and Norethindrone Acetate are available — ask your pharmacist.

Is Loestrin 24 Fe available over the counter?

No. Loestrin 24 Fe is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.

What forms does Loestrin 24 Fe come in?

Loestrin 24 Fe is currently marketed as tablet, per the FDA's National Drug Code Directory.

Is Loestrin 24 Fe FDA-registered?

Loestrin 24 Fe is on record with the U.S. FDA under application number NDA021871. You can verify this on its official FDA label.