juvisync

Foods & drinks to be careful with

Well-established interactions for this medicine’s drug class, summarized from public health authorities. General information, not medical advice — always confirm with your pharmacist or the label.

• Grapefruit & grapefruit juice

  Watch out for: grapefruit and grapefruit juice (and, for some drugs, Seville oranges).

  Grapefruit blocks a gut enzyme (CYP3A4) that normally breaks this medicine down, so more of it can enter your blood — raising the risk of side effects.

  What to do: Avoid grapefruit and grapefruit juice with this medicine unless your pharmacist or the label says it's fine — check, because not every drug in a class is affected the same way.

  Source: Grapefruit Juice and Some Drugs Don't Mix — U.S. FDA

How long does Simvastatin and Sitagliptin Phosphate stay in your body?

The elimination half-life of simvastatin and sitagliptin phosphate is about 2 hours (short) in typical adults — the time it takes the body to clear about half of it. As a rule of thumb, a medicine is mostly gone after roughly 4 to 5 half-lives, though this varies from person to person with age and kidney or liver function. The FDA/DailyMed simvastatin label does not print an explicit numeric elimination half-life; it states plasma total radioactivity peaks at 4 hours and falls to about 10% of peak by 12 hours postdose. Published pharmacokinetics put the parent drug's elimination half-life at roughly 2 hours (some studies show wide individual variation, up to ~6 h mean with a 2-29 h range). Simvastatin's active beta-hydroxyacid metabolite (simvastatin acid) has a similar, NOT longer, half-life of about 1.9 hours, so there is no long-lived active metabolite to worry about.

This is general information, not medical advice. It doesn’t tell you when a drug test would read negative (tests detect substances for different, often longer, windows) or when it’s safe to take another dose — ask your pharmacist or prescriber. Source: Simvastatin tablet, film coated — DailyMed (FDA label), Clinical Pharmacology / Pharmacokinetics.

Frequently asked questions

How is Juvisync rated?

pharmaranks gives Juvisync a composite score of 3.5 out of 5, currently based on 1 weighted source (FDA regulatory recall-safety data weighted highest). See our methodology at /how-we-rate.

How much does Juvisync cost?

Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $0.93 for 30, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins.

Is there a coupon or discount for Juvisync?

pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Juvisync. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.

Who makes Juvisync?

Juvisync is marketed by Merck Sharp Dohme. You can see Merck Sharp Dohme's full profile, rating, and other products on pharmaranks.

Is Juvisync a brand-name or generic drug?

Juvisync is a brand-name product with the active ingredient Simvastatin and Sitagliptin Phosphate.

Is Juvisync available over the counter?

No. Juvisync is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.

What forms does Juvisync come in?

Juvisync is currently marketed as tablet, per the FDA's National Drug Code Directory.

Is Juvisync FDA-registered?

Juvisync is on record with the U.S. FDA under application number NDA202343. You can verify this on its official FDA label.

Has Juvisync been recalled by the FDA?

Juvisync has no FDA recalls recorded under its own application in the openFDA enforcement database. Its recall-safety score reflects its manufacturer's overall recall record. This is general reference, not medical advice — check the FDA recall database for the latest alerts.

Is Juvisync safe?

There's no single safe-or-not verdict. pharmaranks gives Juvisync a recall-safety score of 70/100, based on its FDA recall history (no recalls under its own FDA application) — not an efficacy or side-effect rating. Review its FDA-label side effects and warnings before use, and always consult a licensed professional.