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intermezzo

Intermezzo (Zolpidem Tartrate) is a gamma-aminobutyric acid a receptor positive modulator used to treat Sleep Initiation and Maintenance Disorders.

Zolpidem Tartrate · by Purdue Pharma

Available as a generic: Zolpidem Tartrate

Not yet rated· sourced from the FDA label
Rated against independent regulatory sources·Last updated June 7, 2026·How we rate
Verified againstopenFDANIH DailyMedRxClass

Key facts

Active ingredient
Zolpidem Tartrate
Form
Tablet
Strength
Zolpidem Tartrate 1.75MG · Zolpidem Tartrate 3.5MG
Type
Prescription (Rx)
Brand or generic
Brand-name
Manufacturer
Purdue Pharma
Half-life
about 2.5 hours (mean 2.5-2.6 hours; range roughly 1.4 to 4.5 hours) in healthy adults (how long it stays in your system)
What the pharmacy pays
~$1.04 for 30 — not your price
FDA application
NDA022328
Availability
Discontinued (per FDA)

How long does Zolpidem Tartrate stay in your body?

The elimination half-life of zolpidem tartrate is about 2.5 hours (mean 2.5-2.6 hours; range roughly 1.4 to 4.5 hours) in healthy adults — the time it takes the body to clear about half of it. As a rule of thumb, a medicine is mostly gone after roughly 4 to 5 half-lives, though this varies from person to person with age and kidney or liver function. All zolpidem metabolites are inactive, so no active metabolite extends its effect; however, the half-life is much longer in people with liver cirrhosis (about 10 hours, up to ~26) and modestly longer in adults over 70, so it varies by population.

This is general information, not medical advice. It doesn’t tell you when a drug test would read negative (tests detect substances for different, often longer, windows) or when it’s safe to take another dose — ask your pharmacist or prescriber. Source: ZOLPIDEM TARTRATE tablet, film coated — DailyMed (Clinical Pharmacology, Pharmacokinetics).

Drug class

May treat (source: NIH RxClass)

See how Intermezzo ranks — best-rated gamma-aminobutyric acid a receptor positive modulator for:

Dosage forms

Tablet

The forms currently marketed in the U.S., per the FDA National Drug Code Directory.

Ways to save

Ask for the generic

Same active ingredient, far cheaper. Is there a generic? →

Request a 90-day supply

Bulk fills usually lower the per-dose price vs monthly refills.

Use copay cards

Manufacturer copay cards & patient-assistance programs — especially for brand drugs.

Compare alternatives

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Frequently asked questions

What does Intermezzo treat?
Intermezzo (Zolpidem Tartrate) may be used to treat sleep initiation and maintenance disorders, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.
How much does Intermezzo cost?
Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $1.04 for 30, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins.
Is there a coupon or discount for Intermezzo?
pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Intermezzo. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
Who makes Intermezzo?
Intermezzo is marketed by Purdue Pharma. You can see Purdue Pharma's full profile, rating, and other products on pharmaranks.
Is Intermezzo a brand-name or generic drug?
Intermezzo is a brand-name product with the active ingredient Zolpidem Tartrate. Lower-cost generic equivalents containing Zolpidem Tartrate are available — ask your pharmacist.
Is Intermezzo available over the counter?
No. Intermezzo is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
What forms does Intermezzo come in?
Intermezzo is currently marketed as tablet, per the FDA's National Drug Code Directory.
What class of drug is Intermezzo?
Intermezzo is classified as gamma-aminobutyric acid a receptor positive modulator, gamma-aminobutyric acid-ergic agonist, per the FDA's Established Pharmacologic Class.
Is Intermezzo FDA-registered?
Intermezzo is on record with the U.S. FDA under application number NDA022328. You can verify this on its official FDA label.

Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.

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