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hylorel

Hylorel (Guanadrel Sulfate) is a medication used to treat Hypertension.

Guanadrel Sulfate · by Pharmacia and Upjohn

Not yet rated· sourced from the FDA label
Rated against independent regulatory sources·Last updated June 7, 2026·How we rate
Verified againstopenFDANIH DailyMedRxClass
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Key facts

Active ingredient
Guanadrel Sulfate
Form
Tablet
Strength
Guanadrel Sulfate 10MG · Guanadrel Sulfate 25MG
Type
Prescription (Rx)
Brand or generic
Brand-name
May treat
hypertension
FDA application
NDA018104
Availability
Discontinued (per FDA)

May treat (source: NIH RxClass)

Dosage forms

Tablet

The forms currently marketed in the U.S., per the FDA National Drug Code Directory.

Ways to save

Ask for the generic

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Request a 90-day supply

Bulk fills usually lower the per-dose price vs monthly refills.

Use copay cards

Manufacturer copay cards & patient-assistance programs — especially for brand drugs.

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Frequently asked questions

What does Hylorel treat?
Hylorel (Guanadrel Sulfate) may be used to treat hypertension, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.
Is there a coupon or discount for Hylorel?
pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Hylorel. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
Who makes Hylorel?
Hylorel is marketed by Pharmacia and Upjohn. You can see Pharmacia and Upjohn's full profile, rating, and other products on pharmaranks.
Is Hylorel a brand-name or generic drug?
Hylorel is a brand-name product with the active ingredient Guanadrel Sulfate.
Is Hylorel available over the counter?
No. Hylorel is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
What forms does Hylorel come in?
Hylorel is currently marketed as tablet, per the FDA's National Drug Code Directory.
Is Hylorel FDA-registered?
Hylorel is on record with the U.S. FDA under application number NDA018104. You can verify this on its official FDA label.

Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.

What people report to the FDA about GUANADREL SULFATE

The FDA Adverse Event Reporting System (FAERS) collects reports from patients and clinicians. It holds 2 reports naming GUANADREL SULFATE — the active ingredient in Hylorel, and the FDA flagged 50% of those reports as serious. The effects reported most often — leaving out reports about overdose, misuse or the condition being treated, which dominate the raw list for common medicines:

  • abdominal discomfort1 reports
  • arthralgia1 reports
  • blood creatinine increased1 reports
  • fall1 reports
  • localised infection1 reports
  • musculoskeletal disorder1 reports
  • osteoarthritis1 reports
  • palpitations1 reports

Read these as a signal, not a rate. A report does not mean GUANADREL SULFATE caused the effect — anyone can file one, and many describe people taking several medicines for several conditions. Crucially there is no denominator: FAERS does not record how many people took the drug, so these counts cannot be turned into “X% of patients” — a bigger number often just means a more widely used or more talked-about drug. Duplicates exist, and publicity drives reporting. For what is actually established, read the FDA label.

Source: openFDA drug/event (FAERS), retrieved September 25, 2026.

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