glofil-125
Glofil-125 (Iothalamate Sodium I-125) is a radioactive diagnostic agent.
Iothalamate Sodium I-125 · by Isotex
Key facts
- Active ingredient
- Iothalamate Sodium I-125
- Drug class
- Radioactive Diagnostic Agent
- Form
- Injectable
- Strength
- Iothalamate Sodium I-125 250-300uCi/ML
- Type
- Prescription (Rx)
- Brand or generic
- Brand-name
- Manufacturer
- Isotex
- FDA application
- NDA017279
What is Glofil-125?
From the FDA label:General GLOFIL-125 (Sodium Iothalamate I-125 Injection) is a sterile, nonpyrogenic aqueous injection containing approximately 1 mg sodium iothalamate per mL, and 0.9 percent benzyl alcohol as a preservative. The radioactive concentration of the material is 250-300 µCi/mL as of the calibration date. Sodium bicarbonate and hydrochloric acid are present for pH adjustment.
How to use
Dosage The suggested dose range employed in the average patient (70 kg) is as follows: Continuous intravenous infusion: 20 to 100 μCi (0.74-3.7 megabecquerels) (Sigman, et al (1) method). Single intravenous injection: 10 to 30 µCi (0.37-1.11 megabecquerels) Cohen, et al (2) method) The patient dose should be measured by a suitable radioactivity calibration system immediately prior to administration. Technique Continuous intravenous infusion Sigman 1 method I. Preparation: Adequate diuresis (a urine flow exceeding 3 mL/min.) is established, preferably by an oral water load of 1,500 mL two hours prior to the beginning of the clearance study. 2. It is not necessary to withhold breakfast or admit the patient the night before. II. Procedure: After the establishment of adequate diuresis, a number 14 or 16 French Foley catheter is aseptically inserted into the bladder. An intravenous infusion of Lactated Ringers (Hartmanns) solution is started in each arm, one to maintain a site for injection of the GLOFIL-125, the other to serve as a site for serial withdrawal of blood. A two-way stopcock connects the needle and intravenous tubing of each arm. The dose is equally divided into (1) an intravenous priming dose to be injected as is and (2) a sustaining dose to be diluted in 30 to 60 mL of isotonic sodium chloride, depending on how many collection periods are anticipated. The priming…
Side effects
None Reported
Warnings
Important safety information
None known
Who should not take Glofil-125
GLOFIL-125 should not be administered via a central venous line.
Drug class
How this class works, per Radionuclide Imaging in Cancer Medicine - Holland-Frei Cancer Medicine, NCBI Bookshelf.
Dosage forms
Injectable
The forms currently marketed in the U.S., per the FDA National Drug Code Directory.
Ways to save
Ask for the generic
Same active ingredient, far cheaper. Is there a generic? →
Request a 90-day supply
Bulk fills usually lower the per-dose price vs monthly refills.
Use copay cards
Manufacturer copay cards & patient-assistance programs — especially for brand drugs.
Compare alternatives
A same-class option may cost less. See alternatives →
Frequently asked questions
- How does Glofil-125 work?
- Glofil-125 is a radioactive diagnostic agent. A radioactive diagnostic agent is a small dose of a radioactive substance attached to a molecule that travels to a specific organ or tissue. Once there it gives off radiation that a scanner outside the body detects, producing images that show where that tissue is or how it is working.
- Is there a coupon or discount for Glofil-125?
- pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Glofil-125. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
- Who makes Glofil-125?
- Glofil-125 is marketed by Isotex. You can see Isotex's full profile, rating, and other products on pharmaranks.
- Is Glofil-125 a brand-name or generic drug?
- Glofil-125 is a brand-name product with the active ingredient Iothalamate Sodium I-125.
- Is Glofil-125 available over the counter?
- No. Glofil-125 is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
- What forms does Glofil-125 come in?
- Glofil-125 is currently marketed as injectable, per the FDA's National Drug Code Directory.
- What class of drug is Glofil-125?
- Glofil-125 is classified as radioactive diagnostic agent, per the FDA's Established Pharmacologic Class.
- Is Glofil-125 FDA-registered?
- Glofil-125 is on record with the U.S. FDA under application number NDA017279. You can verify this on its official FDA label.
- Is Glofil-125 safe?
- There's no single safe-or-not verdict, and we don't yet have a composite recall-safety score for Glofil-125. Review its FDA-label side effects and warnings below, and always consult a licensed professional.
- What are the side effects of Glofil-125?
- Glofil-125's side effects are taken directly from its FDA label. From the label: None Reported Both common and serious reactions are documented in full on this page. This is general reference from the FDA, not medical advice — always consult a professional.
Clinical content sourced from the FDA label via openFDA (U.S. FDA). View the FDA label on DailyMed → Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.
Reviews
No reviews yet. Be the first to write one.
People also viewed
locametz
Gallium Ga-68 Gozetotide
ammonia n 13
Ammonia N-13
amyvid
Florbetapir F-18
fludeoxyglucose f18
Fludeoxyglucose F-18
gallium ga 68 gozetotide
Gallium Ga-68 Gozetotide
gozellix
Gallium Ga-68 Gozetotide
Compare Glofil-125 head-to-head
More radioactive diagnostic agent drugs
Browse medications A–Z
Research products from A to Z, compare independent ratings, and find alternatives.
glofil-125
New