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flagyl er

Pharmaranks rates Flagyl ER 3.2/5 for recall safety — an independent score from its FDA recall history and its manufacturer's record. Flagyl ER (Metronidazole) is a nitroimidazole antimicrobial used to treat Abscess, Amebiasis, Bacteroides Infections, Bacterial Endocarditis.

Metronidazole · by Pfizer

Available as a generic: Metronidazole

64/100Limited · 1 source

Based on 1 source · Recall-safety score from FDA recall history — this product's own recalls and its manufacturer's record. Not an efficacy or quality rating. methodology →

Rated against independent regulatory sources·Last updated August 19, 2026·How we rate
Verified againstopenFDANIH DailyMedRxClass

Key facts

Active ingredient
Metronidazole
Form
Tablet, extended release
Strength
Metronidazole 750MG
Type
Prescription (Rx)
Brand or generic
Brand-name
Manufacturer
Pfizer
Half-life
about 8 hours (how long it stays in your system)
What the pharmacy pays
~$0.10 per gm — not your price
FDA application
NDA020868
Availability
Discontinued (per FDA)

Foods & drinks to be careful with

Well-established interactions for this medicine’s drug class, summarized from public health authorities. General information, not medical advice — always confirm with your pharmacist or the label.

  • Alcohol

    Watch out for: beer, wine, spirits, and other products containing alcohol.

    Combining alcohol with this antibiotic can cause a disulfiram-like reaction — flushing, nausea, vomiting, headache, and a fast heartbeat.

    What to do: Avoid alcohol while taking it and for a few days after your last dose, as your prescriber or the label directs. Alcohol can hide in some liquid medicines and mouthwashes.

    Source: Metronidazole — MedlinePlus (U.S. National Library of Medicine)

How long does Metronidazole stay in your body?

The elimination half-life of metronidazole is about 8 hours — the time it takes the body to clear about half of it. As a rule of thumb, a medicine is mostly gone after roughly 4 to 5 half-lives, though this varies from person to person with age and kidney or liver function. This is the average for healthy adults with normal kidney and liver function; the half-life is much longer in newborns (roughly 22 to 109 hours, longer the more premature the baby). Metronidazole has an active metabolite (hydroxy-metronidazole) whose levels build up in older adults (40-80% higher) and in severe kidney disease, though the label does not give a separate half-life for it.

This is general information, not medical advice. It doesn’t tell you when a drug test would read negative (tests detect substances for different, often longer, windows) or when it’s safe to take another dose — ask your pharmacist or prescriber. Source: FLAGYL (metronidazole) label, DailyMed.

Drug class

How this class works, per Metronidazole - StatPearls - NCBI Bookshelf.

May treat (source: NIH RxClass)

See how Flagyl ER ranks — best-rated nitroimidazole antimicrobial for:

Dosage forms

Tablet, extended release

The forms currently marketed in the U.S., per the FDA National Drug Code Directory.

Ways to save

Ask for the generic

Same active ingredient, far cheaper. Is there a generic? →

Request a 90-day supply

Bulk fills usually lower the per-dose price vs monthly refills.

Use copay cards

Manufacturer copay cards & patient-assistance programs — especially for brand drugs.

Compare alternatives

A same-class option may cost less. See alternatives →

Frequently asked questions

What does Flagyl ER treat?
Flagyl ER (Metronidazole) may be used to treat abscess, amebiasis, bacteroides infections, bacterial endocarditis, pseudomembranous enterocolitis, giardiasis, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.
How does Flagyl ER work?
Flagyl ER is a nitroimidazole antimicrobial. Nitroimidazole antibiotics (such as metronidazole) are activated inside oxygen-free bacteria and parasites, where they turn into reactive forms that break and destabilize the microbe's DNA. This kills the germ while largely sparing the body's own cells.
How is Flagyl ER rated?
pharmaranks gives Flagyl ER a composite score of 3.2 out of 5, currently based on 1 weighted source (FDA regulatory recall-safety data weighted highest). See our methodology at /how-we-rate.
How much does Flagyl ER cost?
Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $0.10 per gm, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins.
Is there a coupon or discount for Flagyl ER?
pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Flagyl ER. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
Who makes Flagyl ER?
Flagyl ER is marketed by Pfizer. You can see Pfizer's full profile, rating, and other products on pharmaranks.
Is Flagyl ER a brand-name or generic drug?
Flagyl ER is a brand-name product with the active ingredient Metronidazole. Lower-cost generic equivalents containing Metronidazole are available — ask your pharmacist.
Is Flagyl ER available over the counter?
No. Flagyl ER is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
What forms does Flagyl ER come in?
Flagyl ER is currently marketed as tablet, extended release, per the FDA's National Drug Code Directory.
What class of drug is Flagyl ER?
Flagyl ER is classified as nitroimidazole antimicrobial, per the FDA's Established Pharmacologic Class.
Is Flagyl ER FDA-registered?
Flagyl ER is on record with the U.S. FDA under application number NDA020868. You can verify this on its official FDA label.
Has Flagyl ER been recalled by the FDA?
Flagyl ER has no FDA recalls recorded under its own application in the openFDA enforcement database. Its recall-safety score reflects its manufacturer's overall recall record. This is general reference, not medical advice — check the FDA recall database for the latest alerts.
Is Flagyl ER safe?
There's no single safe-or-not verdict. pharmaranks gives Flagyl ER a recall-safety score of 64/100, based on its FDA recall history (no recalls under its own FDA application) — not an efficacy or side-effect rating. Review its FDA-label side effects and warnings before use, and always consult a licensed professional.

Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.

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flagyl er

64/100