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femcon fe

Femcon Fe is a combination medicine containing Ethinyl Estradiol and Norethindrone.

Ethinyl Estradiol and Norethindrone · by Apil

Available as a generic: Norethindrone and Ethinyl Estradiol and Ferrous Fumarate

Not yet rated· sourced from the FDA label
Rated against independent regulatory sources·Last updated June 7, 2026·How we rate
Verified againstopenFDANIH DailyMedRxClass

Key facts

Active ingredient
Ethinyl Estradiol and Norethindrone
Form
Tablet
Strength
Ethinyl Estradiol 0.035MG; Norethindrone 0.4MG **Federal Register Determination That Product was not Discontinued or Withdrawn for Safety or Effectiveness reasons**
Type
Prescription (Rx)
Brand or generic
Brand-name
Manufacturer
Apil
Half-life
about 8 hours (how long it stays in your system)
FDA application
NDA021490
Availability
Discontinued (per FDA)

How long does Ethinyl Estradiol and Norethindrone stay in your body?

The elimination half-life of ethinyl estradiol and norethindrone is about 8 hours — the time it takes the body to clear about half of it. As a rule of thumb, a medicine is mostly gone after roughly 4 to 5 half-lives, though this varies from person to person with age and kidney or liver function. This is the terminal (elimination) half-life, not a distribution phase: the label states "the mean terminal elimination half-life of norethindrone following single dose administration ... is approximately 8 hours," and its single-dose PK table gives t½ = 7.7 ± 0.5 hours (12 healthy women, 0.35 mg, fasting). Norethindrone itself is the active drug, and the label names no active metabolite that outlasts it — it is extensively reduced and then sulfate/glucuronide conjugated, with less than 5% excreted unchanged. Related point for anyone reading a different label: norethindrone ACETATE is a prodrug that is rapidly converted to norethindrone, so norethindrone is the active moiety in those products too. This label does not characterize how the half-life changes in older adults or in kidney or liver impairment — no such pharmacokinetic data is given, so no number can be quoted for those groups (the label does contraindicate use in women with significant liver disease, but that is a safety statement, not a half-life adjustment).

This is general information, not medical advice. It doesn’t tell you when a drug test would read negative (tests detect substances for different, often longer, windows) or when it’s safe to take another dose — ask your pharmacist or prescriber. Source: CAMILA (norethindrone) 0.35 mg tablets — DailyMed label, Clinical Pharmacology / Pharmacokinetics.

Dosage forms

Tablet

The forms currently marketed in the U.S., per the FDA National Drug Code Directory.

Ways to save

Ask for the generic

Same active ingredient, far cheaper. Is there a generic? →

Request a 90-day supply

Bulk fills usually lower the per-dose price vs monthly refills.

Use copay cards

Manufacturer copay cards & patient-assistance programs — especially for brand drugs.

Compare alternatives

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Frequently asked questions

Is there a coupon or discount for Femcon Fe?
pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Femcon Fe. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
Who makes Femcon Fe?
Femcon Fe is marketed by Apil. You can see Apil's full profile, rating, and other products on pharmaranks.
Is Femcon Fe a brand-name or generic drug?
Femcon Fe is a brand-name product with the active ingredient Ethinyl Estradiol and Norethindrone. Lower-cost generic equivalents containing Ethinyl Estradiol and Norethindrone are available — ask your pharmacist.
Is Femcon Fe available over the counter?
No. Femcon Fe is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
What forms does Femcon Fe come in?
Femcon Fe is currently marketed as tablet, per the FDA's National Drug Code Directory.
Is Femcon Fe FDA-registered?
Femcon Fe is on record with the U.S. FDA under application number NDA021490. You can verify this on its official FDA label.

Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.

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