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Embeda is a combination medicine containing Morphine Sulfate and Naltrexone Hydrochloride.

Morphine Sulfate and Naltrexone Hydrochloride · by Alpharma US Pharms

Not yet rated· sourced from the FDA label
Rated against independent regulatory sources·Last updated June 7, 2026·How we rate
Verified againstopenFDANIH DailyMedRxClass

Key facts

Active ingredient
Morphine Sulfate and Naltrexone Hydrochloride
Form
Capsule, extended release
Strength
Morphine Sulfate 100MG; Naltrexone Hydrochloride 4MG **Federal Register Determination That Product was not Discontinued or Withdrawn for Safety or Effectiveness reasons** · Morphine Sulfate 20MG; Naltrexone Hydrochloride 0.8MG **Federal Register Determination That Product was not Discontinued or Withdrawn for Safety or Effectiveness reasons** · Morphine Sulfate 30MG; Naltrexone Hydrochloride 1.2MG **Federal Register Determination That Product was not Discontinued or Withdrawn for Safety or Effectiveness reasons** · Morphine Sulfate 50MG; Naltrexone Hydrochloride 2MG **Federal Register Determination That Product was not Discontinued or Withdrawn for Safety or Effectiveness reasons** · Morphine Sulfate 60MG; Naltrexone Hydrochloride 2.4MG **Federal Register Determination That Product was not Discontinued or Withdrawn for Safety or Effectiveness reasons** · Morphine Sulfate 80MG; Naltrexone Hydrochloride 3.2MG **Federal Register Determination That Product was not Discontinued or Withdrawn for Safety or Effectiveness reasons**
Type
Prescription (Rx)
Brand or generic
Brand-name
Manufacturer
Alpharma US Pharms
Half-life
about 2 hours (how long it stays in your system)
What the pharmacy pays
~$2.62 per ml — not your price
FDA application
NDA022321
Availability
Discontinued (per FDA)

How long does Morphine Sulfate and Naltrexone Hydrochloride stay in your body?

The elimination half-life of morphine sulfate and naltrexone hydrochloride is about 2 hours — the time it takes the body to clear about half of it. As a rule of thumb, a medicine is mostly gone after roughly 4 to 5 half-lives, though this varies from person to person with age and kidney or liver function. Morphine has an active metabolite (morphine-6-glucuronide, M6G) with analgesic activity, and in people with kidney or liver impairment morphine and its metabolites clear more slowly and can accumulate, prolonging effects; some studies with longer plasma sampling report a longer terminal half-life of roughly 15 hours.

This is general information, not medical advice. It doesn’t tell you when a drug test would read negative (tests detect substances for different, often longer, windows) or when it’s safe to take another dose — ask your pharmacist or prescriber. Source: MORPHINE SULFATE tablet — DailyMed (FDA label), Section 12.3 Pharmacokinetics.

Dosage forms

Capsule, extended release

The forms currently marketed in the U.S., per the FDA National Drug Code Directory.

Ways to save

Ask for the generic

Same active ingredient, far cheaper. Is there a generic? →

Request a 90-day supply

Bulk fills usually lower the per-dose price vs monthly refills.

Use copay cards

Manufacturer copay cards & patient-assistance programs — especially for brand drugs.

Compare alternatives

A same-class option may cost less. See alternatives →

Frequently asked questions

How much does Embeda cost?
Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $2.62 per ml, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins.
Is there a coupon or discount for Embeda?
pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Embeda. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
Who makes Embeda?
Embeda is marketed by Alpharma US Pharms. You can see Alpharma US Pharms's full profile, rating, and other products on pharmaranks.
Is Embeda a brand-name or generic drug?
Embeda is a brand-name product with the active ingredient Morphine Sulfate and Naltrexone Hydrochloride.
Is Embeda available over the counter?
No. Embeda is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
What forms does Embeda come in?
Embeda is currently marketed as capsule, extended release, per the FDA's National Drug Code Directory.
Is Embeda FDA-registered?
Embeda is on record with the U.S. FDA under application number NDA022321. You can verify this on its official FDA label.

Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.

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