duzallo

How long does Allopurinol and Lesinurad stay in your body?

The elimination half-life of allopurinol and lesinurad is about 1 to 2 hours (parent drug) — the time it takes the body to clear about half of it. As a rule of thumb, a medicine is mostly gone after roughly 4 to 5 half-lives, though this varies from person to person with age and kidney or liver function. The ~1-2 hour figure is for allopurinol itself, but it barely reflects how long the drug works. Allopurinol is converted to an active metabolite, oxypurinol (oxipurinol / alloxanthine), which is also a xanthine-oxidase inhibitor and is generally believed to mediate allopurinol's uric-acid-lowering action. Oxypurinol has a much longer plasma half-life of about 15 hours, so the therapeutic effect far outlasts the parent. Allopurinol is cleared by glomerular filtration, but oxypurinol is reabsorbed in the kidney tubules; in people with severely impaired renal function (or reduced urate clearance) the oxypurinol half-life is greatly prolonged.

This is general information, not medical advice. It doesn’t tell you when a drug test would read negative (tests detect substances for different, often longer, windows) or when it’s safe to take another dose — ask your pharmacist or prescriber. Source: ZYLOPRIM (allopurinol) tablet — DailyMed FDA label, Clinical Pharmacology / Pharmacokinetics.

Frequently asked questions

How much does Duzallo cost?

Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $1.66 for 30, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins.

Is there a coupon or discount for Duzallo?

pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Duzallo. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.

Who makes Duzallo?

Duzallo is marketed by Ironwood Pharms Inc. You can see Ironwood Pharms Inc's full profile, rating, and other products on pharmaranks.

Is Duzallo a brand-name or generic drug?

Duzallo is a brand-name product with the active ingredient Allopurinol and Lesinurad.

Is Duzallo available over the counter?

No. Duzallo is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.

What forms does Duzallo come in?

Duzallo is currently marketed as tablet, per the FDA's National Drug Code Directory.

Is Duzallo FDA-registered?

Duzallo is on record with the U.S. FDA under application number NDA209203. You can verify this on its official FDA label.