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dextrose 5% and sodium chloride 0.45% in plastic container

Dextrose 5% and Sodium Chloride 0.45% in Plastic Container is a combination medicine containing Dextrose and Sodium Chloride.

Dextrose and Sodium Chloride · by Otsuka Icu Medcl

Not yet rated· sourced from the FDA label
Rated against independent regulatory sources·Last updated June 7, 2026·How we rate
Verified againstopenFDANIH DailyMedRxClass

Key facts

Active ingredient
Dextrose and Sodium Chloride
Form
Injectable
Strength
Dextrose 5GM/100ML; Sodium Chloride 450MG/100ML
Type
Prescription (Rx)
Brand or generic
Brand-name
Manufacturer
Otsuka Icu Medcl
FDA application
NDA017607

What is Dextrose 5% and Sodium Chloride 0.45% in Plastic Container?

From the FDA label:Dextrose and Sodium Chloride Injection, USP solutions are sterile and nonpyrogenic. They are large volume parenteral solutions containing various concentrations and combinations of these drugs in water for injection intended for intravenous administration. See Table for summary of content and characteristics of these solutions. The solutions contain no bacteriostat, antimicrobial agent or added buffer and each is intended only as a single-dose injection. When smaller doses are required the unused portion should be discarded. The solutions are parenteral fluid, nutrient and electrolyte replenishers. Dextrose, USP is chemically designated D-glucose monohydrate (C 6 H 12 O 6 • H 2 O), a hexose sugar freely soluble in water. It has the following structural formula: Sodium Chloride, USP is chemically designated NaCl, a white crystalline powder freely soluble in water. Water for Injection, USP is chemically designated H 2 O. The flexible plastic container is fabricated from a specially formulated polyvinylchloride. Water can permeate from inside the container into the overwrap but not in amounts sufficient to affect the solution significantly. Solutions in contact with the plastic container may leach out certain chemical components from the plastic in very small amounts; however, biological testing was supportive of the safety of the plastic container materials. Exposure to…

How to use

The dose is dependent upon the age, weight and clinical condition of the patient. As reported in the literature, the dosage and constant infusion rate of intravenous dextrose must be selected with caution in pediatric patients, particularly neonates and low birth weight infants, because of the increased risk of hyperglycemia/hypoglycemia. Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit. See PRECAUTIONS . Drug Interactions Additives may be incompatible. Consult with pharmacist, if available. When introducing additives, use aseptic technique, mix thoroughly and do not store.

Side effects

Reactions which may occur because of the solution or the technique of administration include febrile response, infection at the site of injection, venous thrombosis or phlebitis extending from the site of injection, extravasation and hypervolemia. If an adverse reaction does occur, discontinue the infusion, evaluate the patient, institute appropriate therapeutic countermeasures and save the remainder of the fluid for examination if deemed necessary.

Warnings

Important safety information

Solutions containing sodium ions should be used with great care, if at all, in patients with congestive heart failure, severe renal insufficiency and in clinical states in which there exists edema with sodium retention. Excessive administration of potassium-free solutions may result in significant hypokalemia. In patients with diminished renal function, administration of solutions containing sodium ions may result in sodium retention. The intravenous administration of these solutions can cause fluid and/or solute overloading resulting in dilution of serum electrolyte concentrations, overhydration, congested states or pulmonary edema. The risk of dilutional states is inversely proportional to the electrolyte concentrations of administered parenteral solutions. The risk of solute overload causing congested states with peripheral and pulmonary edema is directly proportional to the electrolyte concentrations of such solutions.

Who should not take Dextrose 5% and Sodium Chloride 0.45% in Plastic Container

None known.

Overdose — what happens if you take too much

In the event of overhydration or solute overload, re-evaluate the patient and institute appropriate corrective measures. See WARNINGS , PRECAUTIONS , and ADVERSE REACTIONS .

U.S. Poison Control: call or text 1-800-222-1222 (free, 24/7). In an emergency call 911. From the FDA label; not medical advice.

Dosage forms

Injectable

The forms currently marketed in the U.S., per the FDA National Drug Code Directory.

Ways to save

Ask for the generic

Same active ingredient, far cheaper. Is there a generic? →

Request a 90-day supply

Bulk fills usually lower the per-dose price vs monthly refills.

Use copay cards

Manufacturer copay cards & patient-assistance programs — especially for brand drugs.

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Frequently asked questions

Is there a coupon or discount for Dextrose 5% and Sodium Chloride 0.45% in Plastic Container?
pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Dextrose 5% and Sodium Chloride 0.45% in Plastic Container. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
Who makes Dextrose 5% and Sodium Chloride 0.45% in Plastic Container?
Dextrose 5% and Sodium Chloride 0.45% in Plastic Container is marketed by Otsuka Icu Medcl. You can see Otsuka Icu Medcl's full profile, rating, and other products on pharmaranks.
Is Dextrose 5% and Sodium Chloride 0.45% in Plastic Container a brand-name or generic drug?
Dextrose 5% and Sodium Chloride 0.45% in Plastic Container is a brand-name product with the active ingredient Dextrose and Sodium Chloride.
Is Dextrose 5% and Sodium Chloride 0.45% in Plastic Container available over the counter?
No. Dextrose 5% and Sodium Chloride 0.45% in Plastic Container is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
What forms does Dextrose 5% and Sodium Chloride 0.45% in Plastic Container come in?
Dextrose 5% and Sodium Chloride 0.45% in Plastic Container is currently marketed as injectable, per the FDA's National Drug Code Directory.
Is Dextrose 5% and Sodium Chloride 0.45% in Plastic Container FDA-registered?
Dextrose 5% and Sodium Chloride 0.45% in Plastic Container is on record with the U.S. FDA under application number NDA017607. You can verify this on its official FDA label.
Is Dextrose 5% and Sodium Chloride 0.45% in Plastic Container safe?
There's no single safe-or-not verdict, and we don't yet have a composite recall-safety score for Dextrose 5% and Sodium Chloride 0.45% in Plastic Container. Review its FDA-label side effects and warnings below, and always consult a licensed professional.
What are the side effects of Dextrose 5% and Sodium Chloride 0.45% in Plastic Container?
Dextrose 5% and Sodium Chloride 0.45% in Plastic Container's side effects are taken directly from its FDA label. From the label: Reactions which may occur because of the solution or the technique of administration include febrile response, infection at the site of injection, venous thrombosis or phlebitis extending from the site of injection, extravasation and hypervolemia. If an adverse reaction does occur,… Both common and serious reactions are documented in full on this page. This is general reference from the FDA, not medical advice — always consult a professional.

Clinical content sourced from the FDA label via openFDA (U.S. FDA). View the FDA label on DailyMed → Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.

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