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decadron w/ xylocaine

Pharmaranks rates Decadron W/ Xylocaine 3.5/5 for recall safety — an independent score from its FDA recall history and its manufacturer's record. Decadron W/ Xylocaine is a combination medicine containing Dexamethasone Sodium Phosphate and Lidocaine Hydrochloride.

Dexamethasone Sodium Phosphate and Lidocaine Hydrochloride · by Merck

70/100Limited · 1 source

Based on 1 source · Recall-safety score from FDA recall history — this product's own recalls and its manufacturer's record. Not an efficacy or quality rating. methodology →

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate
Verified againstopenFDANIH DailyMedRxClass

Key facts

Active ingredient
Dexamethasone Sodium Phosphate and Lidocaine Hydrochloride
Form
Injectable
Strength
Dexamethasone Sodium Phosphate EQ 4MG PHOSPHATE/ML; Lidocaine Hydrochloride 10MG/ML
Type
Prescription (Rx)
Brand or generic
Brand-name
Manufacturer
Merck
Half-life
about 4 hours (how long it stays in your system)
What the pharmacy pays
~$0.23 per ml — not your price
FDA application
NDA013334
Availability
Discontinued (per FDA)

How long does Dexamethasone Sodium Phosphate and Lidocaine Hydrochloride stay in your body?

The elimination half-life of dexamethasone sodium phosphate and lidocaine hydrochloride is about 4 hours — the time it takes the body to clear about half of it. As a rule of thumb, a medicine is mostly gone after roughly 4 to 5 half-lives, though this varies from person to person with age and kidney or liver function. This is the plasma (terminal) elimination half-life — the label states the mean terminal half-life is 4 hours. Dexamethasone's anti-inflammatory/biologic effect lasts far longer than its blood levels (commonly cited biologic half-life ~36-54 hours), which is why it is dosed less often than the short plasma half-life implies; the drug is largely cleared from the blood within about a day (roughly 4-5 half-lives, ~1 day), but this clearance window is not the same as a drug-test detection window. Dexamethasone is ~77% protein-bound and metabolized by CYP3A4 (renal excretion is less than 10% of clearance), so strong CYP3A4 inhibitors/inducers can lengthen or shorten exposure. The manufacturer notes the effect of renal or hepatic impairment on its pharmacokinetics has not been formally studied.

This is general information, not medical advice. It doesn’t tell you when a drug test would read negative (tests detect substances for different, often longer, windows) or when it’s safe to take another dose — ask your pharmacist or prescriber. Source: HEMADY (dexamethasone) tablets — FDA label, Clinical Pharmacology (DailyMed).

Dosage forms

Injectable

The forms currently marketed in the U.S., per the FDA National Drug Code Directory.

Ways to save

Ask for the generic

Same active ingredient, far cheaper. Is there a generic? →

Request a 90-day supply

Bulk fills usually lower the per-dose price vs monthly refills.

Use copay cards

Manufacturer copay cards & patient-assistance programs — especially for brand drugs.

Compare alternatives

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Frequently asked questions

How is Decadron W/ Xylocaine rated?
pharmaranks gives Decadron W/ Xylocaine a composite score of 3.5 out of 5, currently based on 1 weighted source (FDA regulatory recall-safety data weighted highest). See our methodology at /how-we-rate.
How much does Decadron W/ Xylocaine cost?
Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $0.23 per ml, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins.
Is there a coupon or discount for Decadron W/ Xylocaine?
pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Decadron W/ Xylocaine. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
Who makes Decadron W/ Xylocaine?
Decadron W/ Xylocaine is marketed by Merck. You can see Merck's full profile, rating, and other products on pharmaranks.
Is Decadron W/ Xylocaine a brand-name or generic drug?
Decadron W/ Xylocaine is a brand-name product with the active ingredient Dexamethasone Sodium Phosphate and Lidocaine Hydrochloride.
Is Decadron W/ Xylocaine available over the counter?
No. Decadron W/ Xylocaine is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
What forms does Decadron W/ Xylocaine come in?
Decadron W/ Xylocaine is currently marketed as injectable, per the FDA's National Drug Code Directory.
Is Decadron W/ Xylocaine FDA-registered?
Decadron W/ Xylocaine is on record with the U.S. FDA under application number NDA013334. You can verify this on its official FDA label.
Has Decadron W/ Xylocaine been recalled by the FDA?
Decadron W/ Xylocaine has no FDA recalls recorded under its own application in the openFDA enforcement database. Its recall-safety score reflects its manufacturer's overall recall record. This is general reference, not medical advice — check the FDA recall database for the latest alerts.
Is Decadron W/ Xylocaine safe?
There's no single safe-or-not verdict. pharmaranks gives Decadron W/ Xylocaine a recall-safety score of 70/100, based on its FDA recall history (no recalls under its own FDA application) — not an efficacy or side-effect rating. Review its FDA-label side effects and warnings before use, and always consult a licensed professional.

Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.

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decadron w/ xylocaine

70/100