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Pharmaranks rates Cylert 3.6/5 for recall safety — an independent score from its FDA recall history and its manufacturer's record. Cylert (Pemoline) is a medication used to treat Attention Deficit Disorder with Hyperactivity, Narcolepsy.

Pemoline · by Abbott

72/100Limited · 1 source

Based on 1 source · Recall-safety score from FDA recall history — this product's own recalls and its manufacturer's record. Not an efficacy or quality rating. methodology →

Rated against independent regulatory sources·Last updated October 10, 2026·How we rate
Verified againstopenFDANIH DailyMedRxClass

Key facts

Active ingredient
Pemoline
Form
Tablet
Strength
Pemoline 18.75MG · Pemoline 37.5MG · Pemoline 75MG
Type
Prescription (Rx)
Brand or generic
Brand-name
Manufacturer
Abbott
FDA application
NDA016832
Availability
Discontinued (per FDA)

May treat (source: NIH RxClass)

Dosage forms

Tablet

The forms currently marketed in the U.S., per the FDA National Drug Code Directory.

Ways to save

Ask for the generic

Same active ingredient, far cheaper. Is there a generic? →

Request a 90-day supply

Bulk fills usually lower the per-dose price vs monthly refills.

Use copay cards

Manufacturer copay cards & patient-assistance programs — especially for brand drugs.

Compare alternatives

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Frequently asked questions

What does Cylert treat?
Cylert (Pemoline) may be used to treat attention deficit disorder with hyperactivity, narcolepsy, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.
How is Cylert rated?
pharmaranks gives Cylert a composite score of 3.6 out of 5, currently based on 1 weighted source (FDA regulatory recall-safety data weighted highest). See our methodology at /how-we-rate.
Is there a coupon or discount for Cylert?
pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Cylert. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
Who makes Cylert?
Cylert is marketed by Abbott. You can see Abbott's full profile, rating, and other products on pharmaranks.
Is Cylert a brand-name or generic drug?
Cylert is a brand-name product with the active ingredient Pemoline.
Is Cylert available over the counter?
No. Cylert is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
What forms does Cylert come in?
Cylert is currently marketed as tablet, per the FDA's National Drug Code Directory.
Is Cylert FDA-registered?
Cylert is on record with the U.S. FDA under application number NDA016832. You can verify this on its official FDA label.
Has Cylert been recalled by the FDA?
Cylert has no FDA recalls recorded under its own application in the openFDA enforcement database. Its recall-safety score reflects its manufacturer's overall recall record. This is general reference, not medical advice — check the FDA recall database for the latest alerts.
Is Cylert safe?
There's no single safe-or-not verdict. pharmaranks gives Cylert a recall-safety score of 72/100, based on its FDA recall history (no recalls under its own FDA application) — not an efficacy or side-effect rating. Review its FDA-label side effects and warnings before use, and always consult a licensed professional.

Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.

What people report to the FDA about PEMOLINE

The FDA Adverse Event Reporting System (FAERS) collects reports from patients and clinicians. It holds 68 reports naming PEMOLINE — the active ingredient in Cylert, and the FDA flagged 93% of those reports as serious. The effects reported most often — leaving out reports about overdose, misuse or the condition being treated, which dominate the raw list for common medicines:

  • psychotic disorder6 reports
  • depression5 reports
  • drug intolerance5 reports
  • mania5 reports
  • narcolepsy5 reports
  • sedation5 reports
  • bradycardia4 reports
  • acute hepatic failure3 reports

Read these as a signal, not a rate. A report does not mean PEMOLINE caused the effect — anyone can file one, and many describe people taking several medicines for several conditions. Crucially there is no denominator: FAERS does not record how many people took the drug, so these counts cannot be turned into “X% of patients” — a bigger number often just means a more widely used or more talked-about drug. Duplicates exist, and publicity drives reporting. For what is actually established, read the FDA label.

Source: openFDA drug/event (FAERS), retrieved September 25, 2026.

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