How is Cipro Hc rated?

pharmaranks gives Cipro Hc a composite score of 3.4 out of 5, currently based on 1 weighted source (FDA regulatory recall-safety data weighted highest). See our methodology at /how-we-rate.

How much does Cipro Hc cost?

Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $3.71 for 30, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins.

Is there a coupon or discount for Cipro Hc?

pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Cipro Hc. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.

Cipro Hc is marketed by Sandoz. You can see Sandoz's full profile, rating, and other products on pharmaranks.

Is Cipro Hc a brand-name or generic drug?

Cipro Hc is a brand-name product with the active ingredient Ciprofloxacin Hydrochloride and Hydrocortisone.

Is Cipro Hc available over the counter?

No. Cipro Hc is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.

What forms does Cipro Hc come in?

Cipro Hc is currently marketed as drops, per the FDA's National Drug Code Directory.

Is Cipro Hc FDA-registered?

Cipro Hc is on record with the U.S. FDA under application number NDA020805. You can verify this on its official FDA label.

Has Cipro Hc been recalled by the FDA?

Cipro Hc has no FDA recalls recorded under its own application in the openFDA enforcement database. Its recall-safety score reflects its manufacturer's overall recall record. This is general reference, not medical advice — check the FDA recall database for the latest alerts.

There's no single safe-or-not verdict. pharmaranks gives Cipro Hc a recall-safety score of 68/100, based on its FDA recall history (no recalls under its own FDA application) — not an efficacy or side-effect rating. Review its FDA-label side effects and warnings before use, and always consult a licensed professional.

cipro hc

Pharmaranks rates Cipro Hc 3.4/5 for recall safety — an independent score from its FDA recall history and its manufacturer's record. Cipro Hc is a combination medicine containing Ciprofloxacin Hydrochloride and Hydrocortisone.

Ciprofloxacin Hydrochloride and Hydrocortisone · by Sandoz

68/100Limited · 1 source

Based on 1 source · Recall-safety score from FDA recall history — this product's own recalls and its manufacturer's record. Not an efficacy or quality rating. methodology →

Rated against independent regulatory sources·Last updated August 20, 2026·How we rate

Verified againstopenFDANIH DailyMedRxClass

~$3.71 /30

See alternatives →

Key facts

Active ingredient: Ciprofloxacin Hydrochloride and Hydrocortisone
Form: Drops
Strength: Ciprofloxacin Hydrochloride EQ 0.2% Base; Hydrocortisone 1%
Type: Prescription (Rx)
Brand or generic: Brand-name
Manufacturer: Sandoz
Half-life: about 1.5 hours (how long it stays in your system)
What the pharmacy pays: ~$3.71 for 30 — not your price
FDA application: NDA020805

What is Cipro Hc?

From the FDA label:CIPRO ® HC OTIC (ciprofloxacin hydrochloride and hydrocortisone otic suspension) contains the synthetic broad spectrum antibacterial agent, ciprofloxacin hydrochloride, combined with the anti-inflammatory corticosteroid, hydrocortisone, in a preserved, nonsterile suspension for otic use. Each mL of CIPRO ® HC OTIC contains ciprofloxacin hydrochloride (equivalent to 2 mg ciprofloxacin), 10 mg hydrocortisone, and 9 mg benzyl alcohol as a preservative. The inactive ingredients are polyvinyl alcohol, sodium chloride, sodium acetate, glacial acetic acid, phospholipon 90H (modified lecithin), polysorbate, and purified water. Sodium hydroxide or hydrochloric acid may be added for adjustment of pH. Ciprofloxacin, a fluoroquinolone, is available as the monohydrochloride monohydrate salt of 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid. Its empirical formula is C 17 H 18 FN 3 O 3 •HCI•H 2 O and its chemical structure is as follows: Hydrocortisone, pregn-4-ene-3, 20-dione, 11, 17, 21-trihydroxy-(11(β)-, is an anti-inflammatory corticosteroid. Its empirical formula is C 21 H 30 O 5 and its chemical structure is: Ciprofloxacin chemical structure Hydrocortisone chemical structure

How to use

For children (age 1 year and older) and adults, 3 drops of the suspension should be instilled into the affected ear twice daily for seven days. The suspension should be warmed by holding the bottle in the hand for 1-2 minutes to avoid the dizziness, which may result from the instillation of a cold solution into the ear canal. The patient should lie with the affected ear upward and then the drops should be instilled. This position should be maintained for 30-60 seconds to facilitate penetration of the drops into the ear. Repeat, if necessary, for the opposite ear. Discard unused portion after therapy is completed.

Side effects

In Phase 3 clinical trials, a total of 564 patients were treated with CIPRO ® HC OTIC. Adverse events with at least remote relationship to treatment included headache (1.2%) and pruritus (0.4%). The following treatment-related adverse events were each reported in a single patient: migraine, hypesthesia, paresthesia, fungal dermatitis, cough, rash, urticaria, and alopecia. The following reactions have been identified during post-approval use of CIPRO ® HC OTIC in clinical practice. Because they are reported voluntarily from a population of unknown size, estimates of frequency cannot be made. The reactions, which have been chosen for inclusion due to either their seriousness, frequency of reporting, possible causal connection to CIPRO ® HC OTIC, or a combination of these factors, include: dizziness, ear canal erythema, ear congestion, hypoacusis, and medication residue.

Warnings

Important safety information

NOT FOR OPHTHALMIC USE. NOT FOR INJECTION. CIPRO ® HC OTIC should be discontinued at the first appearance of a skin rash or any other sign of hypersensitivity. Serious and occasionally fatal hypersensitivity (anaphylactic) reactions, some following the first dose, have been reported in patients receiving systemic quinolones. Serious acute hypersensitivity reactions may require immediate emergency treatment. The dropper cap contains natural rubber (latex) which may cause severe allergic reactions.

Who should not take Cipro Hc

CIPRO ® HC OTIC is contraindicated in persons with a history of hypersensitivity to hydrocortisone, ciprofloxacin, or any member of the quinolone class of antimicrobial agents. This nonsterile product should not be used if the tympanic membrane is known or suspected to be perforated. Use of this product is contraindicated in viral infections of the external canal, including varicella and herpes simplex infections.

How long does Ciprofloxacin Hydrochloride and Hydrocortisone stay in your body?

The elimination half-life of ciprofloxacin hydrochloride and hydrocortisone is about 1.5 hours — the time it takes the body to clear about half of it. As a rule of thumb, a medicine is mostly gone after roughly 4 to 5 half-lives, though this varies from person to person with age and kidney or liver function. This is the plasma (terminal) elimination half-life; the FDA label states "The terminal half-life of hydrocortisone is about 1.5 hours following intravenous and oral dosing of hydrocortisone tablets" in healthy adults, so roughly 90% of a dose clears within about 8 hours and nearly all within ~12 hours. Hydrocortisone is not a prodrug, but its half-life measures how fast the drug leaves the blood, not how long its effects last: as a short-acting glucocorticoid its biological (tissue) effect on the body persists well beyond blood clearance, and this short plasma half-life is why oral replacement is usually dosed 2-3 times a day. Because hydrocortisone is metabolized in the liver, significant liver impairment can slow clearance; the label does not give a specific half-life adjustment for age, kidney, or liver function. Half-life is not the same as a drug-test detection window.

This is general information, not medical advice. It doesn’t tell you when a drug test would read negative (tests detect substances for different, often longer, windows) or when it’s safe to take another dose — ask your pharmacist or prescriber. Source: ALKINDI SPRINKLE (hydrocortisone) oral granules — FDA prescribing information, DailyMed.

Dosage forms

Drops

The forms currently marketed in the U.S., per the FDA National Drug Code Directory.

Ways to save

Ask for the generic

Same active ingredient, far cheaper. Is there a generic? →

Request a 90-day supply

Bulk fills usually lower the per-dose price vs monthly refills.

Use copay cards

Manufacturer copay cards & patient-assistance programs — especially for brand drugs.

Compare alternatives

A same-class option may cost less. See alternatives →

Frequently asked questions

How is Cipro Hc rated?: pharmaranks gives Cipro Hc a composite score of 3.4 out of 5, currently based on 1 weighted source (FDA regulatory recall-safety data weighted highest). See our methodology at /how-we-rate.
How much does Cipro Hc cost?: Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $3.71 for 30, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins.
Is there a coupon or discount for Cipro Hc?: pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Cipro Hc. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
Who makes Cipro Hc?: Cipro Hc is marketed by Sandoz. You can see Sandoz's full profile, rating, and other products on pharmaranks.
Is Cipro Hc a brand-name or generic drug?: Cipro Hc is a brand-name product with the active ingredient Ciprofloxacin Hydrochloride and Hydrocortisone.
Is Cipro Hc available over the counter?: No. Cipro Hc is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
What forms does Cipro Hc come in?: Cipro Hc is currently marketed as drops, per the FDA's National Drug Code Directory.
Is Cipro Hc FDA-registered?: Cipro Hc is on record with the U.S. FDA under application number NDA020805. You can verify this on its official FDA label.
Has Cipro Hc been recalled by the FDA?: Cipro Hc has no FDA recalls recorded under its own application in the openFDA enforcement database. Its recall-safety score reflects its manufacturer's overall recall record. This is general reference, not medical advice — check the FDA recall database for the latest alerts.
Is Cipro Hc safe?: There's no single safe-or-not verdict. pharmaranks gives Cipro Hc a recall-safety score of 68/100, based on its FDA recall history (no recalls under its own FDA application) — not an efficacy or side-effect rating. Review its FDA-label side effects and warnings before use, and always consult a licensed professional.
What are the side effects of Cipro Hc?: Cipro Hc's side effects are taken directly from its FDA label. From the label: In Phase 3 clinical trials, a total of 564 patients were treated with CIPRO ® HC OTIC. Adverse events with at least remote relationship to treatment included headache (1.2%) and pruritus (0.4%). The following treatment-related adverse events were each reported in a single patient: migraine,… Both common and serious reactions are documented in full on this page. This is general reference from the FDA, not medical advice — always consult a professional.

Clinical content sourced from the FDA label via openFDA (U.S. FDA). View the FDA label on DailyMed → Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.

Estimate your price

Strength & form

Quantity (tablets/units)

$3.54what the pharmacy pays · 30 units

NADAC (CMS national average) — what the pharmacy paid to acquire this quantity, not what you will be charged. Your price is set after that by your insurer and the pharmacy. Why they differ.

How we rate

methodology →

openFDA / Drugs@FDA66/100· n=23
Regulatoryweight ×1.5

Headline composite68/100

The headline isn't a raw average of the sources above: while data is thin, each source score is pulled toward a neutral 70/100 baseline (a confidence adjustment for sample size), so it firms up toward the raw scores as more data accumulates. how we rate →

See alternatives to CIPRO HC →Is there a generic for CIPRO HC? →