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chloromycetin hydrocortisone

Chloromycetin Hydrocortisone is a combination medicine containing Chloramphenicol and Hydrocortisone Acetate.

Chloramphenicol and Hydrocortisone Acetate · by Parkedale

Not yet rated· sourced from the FDA label
Rated against independent regulatory sources·Last updated June 7, 2026·How we rate
Verified againstopenFDANIH DailyMedRxClass

Key facts

Active ingredient
Chloramphenicol and Hydrocortisone Acetate
Strength
Chloramphenicol 12.5MG/VIAL; Hydrocortisone Acetate 25MG/VIAL
Type
Prescription (Rx)
Brand or generic
Brand-name
Manufacturer
Parkedale
Half-life
about 1.5 hours (how long it stays in your system)
FDA application
NDA050202
Availability
Discontinued (per FDA)

How long does Chloramphenicol and Hydrocortisone Acetate stay in your body?

The elimination half-life of chloramphenicol and hydrocortisone acetate is about 1.5 hours — the time it takes the body to clear about half of it. As a rule of thumb, a medicine is mostly gone after roughly 4 to 5 half-lives, though this varies from person to person with age and kidney or liver function. This is the plasma (terminal) elimination half-life; the FDA label states "The terminal half-life of hydrocortisone is about 1.5 hours following intravenous and oral dosing of hydrocortisone tablets" in healthy adults, so roughly 90% of a dose clears within about 8 hours and nearly all within ~12 hours. Hydrocortisone is not a prodrug, but its half-life measures how fast the drug leaves the blood, not how long its effects last: as a short-acting glucocorticoid its biological (tissue) effect on the body persists well beyond blood clearance, and this short plasma half-life is why oral replacement is usually dosed 2-3 times a day. Because hydrocortisone is metabolized in the liver, significant liver impairment can slow clearance; the label does not give a specific half-life adjustment for age, kidney, or liver function. Half-life is not the same as a drug-test detection window.

This is general information, not medical advice. It doesn’t tell you when a drug test would read negative (tests detect substances for different, often longer, windows) or when it’s safe to take another dose — ask your pharmacist or prescriber. Source: ALKINDI SPRINKLE (hydrocortisone) oral granules — FDA prescribing information, DailyMed.

Ways to save

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Frequently asked questions

Is there a coupon or discount for Chloromycetin Hydrocortisone?
pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Chloromycetin Hydrocortisone. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
Who makes Chloromycetin Hydrocortisone?
Chloromycetin Hydrocortisone is marketed by Parkedale. You can see Parkedale's full profile, rating, and other products on pharmaranks.
Is Chloromycetin Hydrocortisone a brand-name or generic drug?
Chloromycetin Hydrocortisone is a brand-name product with the active ingredient Chloramphenicol and Hydrocortisone Acetate.
Is Chloromycetin Hydrocortisone available over the counter?
No. Chloromycetin Hydrocortisone is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
Is Chloromycetin Hydrocortisone FDA-registered?
Chloromycetin Hydrocortisone is on record with the U.S. FDA under application number NDA050202. You can verify this on its official FDA label.

Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.

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