bunavail

How long does Buprenorphine Hydrochloride and Naloxone Hydrochloride stay in your body?

The elimination half-life of buprenorphine hydrochloride and naloxone hydrochloride is 30 to 81 minutes (mean 64 ± 12 minutes) — the time it takes the body to clear about half of it. As a rule of thumb, a medicine is mostly gone after roughly 4 to 5 half-lives, though this varies from person to person with age and kidney or liver function. This is the serum elimination half-life in adults with normal organ function; naloxone is metabolized in the liver by glucuronide conjugation (major metabolite naloxone-3-glucuronide, which is inactive) and excreted in urine. The half-life is much longer in neonates (mean 3.1 ± 0.5 hours). Because naloxone's half-life is short — often shorter than that of the opioids it reverses — its effects can wear off before the opioid does, so repeat dosing may be needed. Half-life is a pharmacokinetic elimination measure, not a drug-test detection window.

This is general information, not medical advice. It doesn’t tell you when a drug test would read negative (tests detect substances for different, often longer, windows) or when it’s safe to take another dose — ask your pharmacist or prescriber. Source: NALOXONE HYDROCHLORIDE injection — DailyMed FDA label.

Frequently asked questions

How much does Bunavail cost?

Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $671.29 for 30, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins.

Is there a coupon or discount for Bunavail?

pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Bunavail. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.

Who makes Bunavail?

Bunavail is marketed by Bdsi. You can see Bdsi's full profile, rating, and other products on pharmaranks.

Is Bunavail a brand-name or generic drug?

Bunavail is a brand-name product with the active ingredient Buprenorphine Hydrochloride and Naloxone Hydrochloride. Lower-cost generic equivalents containing Buprenorphine Hydrochloride and Naloxone Hydrochloride are available — ask your pharmacist.

Is Bunavail available over the counter?

No. Bunavail is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.

What forms does Bunavail come in?

Bunavail is currently marketed as film, per the FDA's National Drug Code Directory.

Is Bunavail FDA-registered?

Bunavail is on record with the U.S. FDA under application number NDA205637. You can verify this on its official FDA label.