Skip to content
ppharmaranks
Menu
Alcon logo

bss

Bss is a combination medicine containing Calcium Chloride, Magnesium Chloride, Potassium Chloride, Sodium Acetate, Sodium Chloride, and Sodium Citrate.

Calcium Chloride and Magnesium Chloride and Potassium Chloride and Sodium Acetate and Sodium Chloride and Sodium Citrate · by Alcon

Not yet rated· sourced from the FDA label
Rated against independent regulatory sources·Last updated June 7, 2026·How we rate
Verified againstopenFDANIH DailyMedRxClass

Key facts

Active ingredient
Calcium Chloride and Magnesium Chloride and Potassium Chloride and Sodium Acetate and Sodium Chloride and Sodium Citrate
Form
Solution
Strength
Calcium Chloride 0.48MG/ML; Magnesium Chloride 0.3MG/ML; Potassium Chloride 0.75MG/ML; Sodium Acetate 3.9MG/ML; Sodium Chloride 6.4MG/ML; Sodium Citrate 1.7MG/ML
Type
Prescription (Rx)
Brand or generic
Brand-name
Manufacturer
Alcon
What the pharmacy pays
~$0.04 per ml — not your price
FDA application
NDA020742

What is Bss?

From the FDA label:BSS ™ Sterile Irrigating Solution is a sterile balanced salt solution, each mL containing sodium chloride (NaCl) 0.64%, potassium chloride (KCl) 0.075%, calcium chloride dihydrate (CaCl 2 •2H 2 O) 0.048%, magnesium chloride hexahydrate (MgCl 2 •6H 2 O) 0.03%, sodium acetate trihydrate (C 2 H 3 NaO 2 •3H 2 O) 0.39%, sodium citrate dihydrate (C 6 H 5 Na 3 O 7 •2H 2 O) 0.17%, sodium hydroxide and/or hydrochloric acid (to adjust pH), and water for injection. The pH is approximately 7.5. The osmolality is approximately 300 mOsm/Kg.

How to use

This irrigating solution should be used according to standard format for each surgical procedure. Follow directions of the particular administration set to be used. Remove the outer overwrap. Clean and disinfect the rubber stopper by using a sterile alcohol wipe. Insert the spike aseptically into the bag through the target area of the rubber stopper. Allow the fluid to flow and remove air from the tubing before irrigation begins.

Side effects

Irrigation or any other trauma to the corneal endothelium may result in corneal swelling or bullous keratopathy. Post-operative inflammatory reactions as well as incidents of corneal edema and corneal decompensation have been reported.

Warnings

Important safety information

Do not use unless product is clear, seal is intact, and container is undamaged. Do not use if product is discolored or contains a precipitate. SINGLE patient use only. The contents of this bag should not be used in more than one patient. This solution contains no preservative, unused contents should be discarded.

Dosage forms

Solution

The forms currently marketed in the U.S., per the FDA National Drug Code Directory.

Ways to save

Ask for the generic

Same active ingredient, far cheaper. Is there a generic? →

Request a 90-day supply

Bulk fills usually lower the per-dose price vs monthly refills.

Use copay cards

Manufacturer copay cards & patient-assistance programs — especially for brand drugs.

Compare alternatives

A same-class option may cost less. See alternatives →

Frequently asked questions

How much does Bss cost?
Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $0.04 per ml, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins.
Is there a coupon or discount for Bss?
pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Bss. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
Who makes Bss?
Bss is marketed by Alcon. You can see Alcon's full profile, rating, and other products on pharmaranks.
Is Bss a brand-name or generic drug?
Bss is a brand-name product with the active ingredient Calcium Chloride and Magnesium Chloride and Potassium Chloride and Sodium Acetate and Sodium Chloride and Sodium Citrate.
Is Bss available over the counter?
No. Bss is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
What forms does Bss come in?
Bss is currently marketed as solution, per the FDA's National Drug Code Directory.
Is Bss FDA-registered?
Bss is on record with the U.S. FDA under application number NDA020742. You can verify this on its official FDA label.
Is Bss safe?
There's no single safe-or-not verdict, and we don't yet have a composite recall-safety score for Bss. Review its FDA-label side effects and warnings below, and always consult a licensed professional.
What are the side effects of Bss?
Bss's side effects are taken directly from its FDA label. From the label: Irrigation or any other trauma to the corneal endothelium may result in corneal swelling or bullous keratopathy. Post-operative inflammatory reactions as well as incidents of corneal edema and corneal decompensation have been reported. Both common and serious reactions are documented in full on this page. This is general reference from the FDA, not medical advice — always consult a professional.

Clinical content sourced from the FDA label via openFDA (U.S. FDA). View the FDA label on DailyMed → Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.

Reviews

No reviews yet. Be the first to write one.

Write a review

Reviews are user opinions, not medical advice. Consult a licensed professional.

People also viewed

Compare Bss head-to-head

Identify a pill by its imprint →Check a drug interaction →Drug recalls →

Browse medications A–Z

Research products from A to Z, compare independent ratings, and find alternatives.