bicillin
Bicillin (Penicillin G Benzathine) is a penicillin-class antibacterial used to treat Actinomycosis, Anthrax, Botulism, Diphtheria.
Penicillin G Benzathine · by Wyeth Ayerst
Key facts
- Active ingredient
- Penicillin G Benzathine
- Drug class
- Penicillin-Class Antibacterial
- Form
- Suspension, Tablet
- Strength
- Penicillin G Benzathine 300,000 UNITS/5ML
- Type
- Prescription (Rx)
- Brand or generic
- Brand-name
- May treat
- actinomycosis, anthrax, botulism
- Manufacturer
- Wyeth Ayerst
- FDA application
- NDA050126
- Availability
- Discontinued (per FDA)
Drug class
May treat (source: NIH RxClass)
- actinomycosis
- anthrax
- botulism
- diphtheria
- empyema
- endocarditis
See how Bicillin ranks — best-rated penicillin-class antibacterial for:
Dosage forms
Suspension and Tablet
The forms currently marketed in the U.S., per the FDA National Drug Code Directory.
Ways to save
Ask for the generic
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Request a 90-day supply
Bulk fills usually lower the per-dose price vs monthly refills.
Use copay cards
Manufacturer copay cards & patient-assistance programs — especially for brand drugs.
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Frequently asked questions
- What does Bicillin treat?
- Bicillin (Penicillin G Benzathine) may be used to treat actinomycosis, anthrax, botulism, diphtheria, empyema, endocarditis, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.
- Is there a coupon or discount for Bicillin?
- pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Bicillin. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
- Who makes Bicillin?
- Bicillin is marketed by Wyeth Ayerst. You can see Wyeth Ayerst's full profile, rating, and other products on pharmaranks.
- Is Bicillin a brand-name or generic drug?
- Bicillin is a brand-name product with the active ingredient Penicillin G Benzathine.
- Is Bicillin available over the counter?
- No. Bicillin is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
- What forms does Bicillin come in?
- Bicillin is currently marketed as suspension and tablet, per the FDA's National Drug Code Directory.
- What class of drug is Bicillin?
- Bicillin is classified as penicillin-class antibacterial, per the FDA's Established Pharmacologic Class.
- Is Bicillin FDA-registered?
- Bicillin is on record with the U.S. FDA under application number NDA050126. You can verify this on its official FDA label.
Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.
What people report to the FDA about PENICILLIN G BENZATHINE
The FDA Adverse Event Reporting System (FAERS) collects reports from patients and clinicians. It holds 512 reports naming PENICILLIN G BENZATHINE — the active ingredient in Bicillin, and the FDA flagged 72% of those reports as serious. The effects reported most often — leaving out reports about overdose, misuse or the condition being treated, which dominate the raw list for common medicines:
- drug hypersensitivity114 reports
- embolia cutis medicamentosa33 reports
- hypersensitivity31 reports
- acute kidney injury30 reports
- rash22 reports
- diarrhoea19 reports
- foetal exposure during pregnancy19 reports
- jarisch-herxheimer reaction18 reports
Read these as a signal, not a rate. A report does not mean PENICILLIN G BENZATHINE caused the effect — anyone can file one, and many describe people taking several medicines for several conditions. Crucially there is no denominator: FAERS does not record how many people took the drug, so these counts cannot be turned into “X% of patients” — a bigger number often just means a more widely used or more talked-about drug. Duplicates exist, and publicity drives reporting. For what is actually established, read the FDA label.
Source: openFDA drug/event (FAERS), retrieved September 25, 2026.
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