atenolol and chlorthalidone

How long does Atenolol and Chlorthalidone stay in your body?

The elimination half-life of atenolol and chlorthalidone is about 40 hours on average (the label reports a mean half-life of 40 hours after a 50–200 mg dose, and an elimination half-life of 53 hours after 50 mg and 60 hours after 100 mg) — the time it takes the body to clear about half of it. As a rule of thumb, a medicine is mostly gone after roughly 4 to 5 half-lives, though this varies from person to person with age and kidney or liver function. This is an older-format label (CLINICAL PHARMACOLOGY, not a PLR §12.3), and it gives its numbers in two ways: a mean half-life of 40 hours across the 50–200 mg dose range, and dose-specific elimination half-lives of 53 hours (50 mg) and 60 hours (100 mg). Only one phase is described, so the figures above are the elimination values the label states — it does not report a separate distribution phase. No active metabolite is described: the label says chlorthalidone is largely excreted unchanged by the kidneys and that data on metabolites and non-renal elimination routes "have yet to be clarified." It is not a prodrug. Do not confuse the half-life with the duration of diuretic effect — the label describes diuresis beginning in about 2.6 hours and continuing up to 72 hours, which is a different measure. The label does NOT quantify how the half-life changes with age, kidney impairment, or liver impairment; it gives no geriatric or renal/hepatic pharmacokinetic numbers. It does warn that cumulative effects of the drug may develop in patients with impaired renal function, and to use caution in severe renal disease and in impaired hepatic function — but it does not state a half-life for those groups, so no number should be inferred for them.

This is general information, not medical advice. It doesn’t tell you when a drug test would read negative (tests detect substances for different, often longer, windows) or when it’s safe to take another dose — ask your pharmacist or prescriber. Source: DailyMed — CHLORTHALIDONE tablet (Clinical Pharmacology).

Frequently asked questions

How is Atenolol and Chlorthalidone rated?

pharmaranks gives Atenolol and Chlorthalidone a composite score of 3.4 out of 5, currently based on 1 weighted source (FDA regulatory recall-safety data weighted highest). See our methodology at /how-we-rate.

How much does Atenolol and Chlorthalidone cost?

Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $0.76 for 30, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins.

Is there a coupon or discount for Atenolol and Chlorthalidone?

pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Atenolol and Chlorthalidone. To pay less, Atenolol and Chlorthalidone is already a generic — usually the lowest-cost version — so the main levers are comparing cash prices between pharmacies and using a pharmacy discount-card service. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.

Who makes Atenolol and Chlorthalidone?

Atenolol and Chlorthalidone is marketed by Aurobindo Pharma Ltd. You can see Aurobindo Pharma Ltd's full profile, rating, and other products on pharmaranks.

Is Atenolol and Chlorthalidone a brand-name or generic drug?

Atenolol and Chlorthalidone is a generic medication; its active ingredient is Atenolol and Chlorthalidone. Generics contain the same active ingredient as the brand-name original and are usually lower cost.

Is Atenolol and Chlorthalidone available over the counter?

No. Atenolol and Chlorthalidone is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.

What forms does Atenolol and Chlorthalidone come in?

Atenolol and Chlorthalidone is currently marketed as tablet, per the FDA's National Drug Code Directory.

Is Atenolol and Chlorthalidone FDA-registered?

Atenolol and Chlorthalidone is on record with the U.S. FDA under application number ANDA074203. You can verify this on its official FDA label.

Has Atenolol and Chlorthalidone been recalled by the FDA?

Atenolol and Chlorthalidone has no FDA recalls recorded under its own application in the openFDA enforcement database. Its recall-safety score reflects its manufacturer's overall recall record. This is general reference, not medical advice — check the FDA recall database for the latest alerts.

Is Atenolol and Chlorthalidone safe?

There's no single safe-or-not verdict. pharmaranks gives Atenolol and Chlorthalidone a recall-safety score of 68/100, based on its FDA recall history (no recalls under its own FDA application) — not an efficacy or side-effect rating. Review its FDA-label side effects and warnings before use, and always consult a licensed professional.