amantadine hydrochloride

How long does Amantadine Hydrochloride stay in your body?

The elimination half-life of amantadine hydrochloride is about 17 hours (range roughly 10 to 25 hours); across studies it has averaged about 16 hours (range 9 to 31 hours) in healthy adults — the time it takes the body to clear about half of it. As a rule of thumb, a medicine is mostly gone after roughly 4 to 5 half-lives, though this varies from person to person with age and kidney or liver function. Amantadine is excreted mostly unchanged in urine, so its half-life depends heavily on kidney function and age. In healthy elderly adults (age 60+) the half-life rises to about 29 hours (range 20 to 41 hours) as clearance falls. In renal impairment the elimination half-life increases two- to threefold or more when creatinine clearance is below 40 mL/min/1.73 m2, and averages about 8 days in patients on chronic maintenance hemodialysis (amantadine is removed only negligibly by hemodialysis). The label describes no active metabolite that outlasts the parent: the main metabolite, N-acetylamantadine (acetylamantadine), has an unknown contribution to efficacy or toxicity, and amantadine is not a prodrug. The label does not separate a distinct distribution phase, so the reported value is the terminal/elimination half-life.

This is general information, not medical advice. It doesn’t tell you when a drug test would read negative (tests detect substances for different, often longer, windows) or when it’s safe to take another dose — ask your pharmacist or prescriber. Source: Amantadine Hydrochloride FDA label (DailyMed) — Clinical Pharmacology, Pharmacokinetics.

Frequently asked questions

What does Amantadine Hydrochloride treat?

Amantadine Hydrochloride (Amantadine Hydrochloride) may be used to treat drug-induced dyskinesia, dystonia, human influenza, parkinson disease, secondary parkinson disease, drug-induced akathisia, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.

How much does Amantadine Hydrochloride cost?

Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $4.67 for 30, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins.

Is there a coupon or discount for Amantadine Hydrochloride?

pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Amantadine Hydrochloride. To pay less, Amantadine Hydrochloride is already a generic — usually the lowest-cost version — so the main levers are comparing cash prices between pharmacies and using a pharmacy discount-card service. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.

Who makes Amantadine Hydrochloride?

Amantadine Hydrochloride is marketed by Ph Health. You can see Ph Health's full profile, rating, and other products on pharmaranks.

Is Amantadine Hydrochloride a brand-name or generic drug?

Amantadine Hydrochloride is a generic medication; its active ingredient is Amantadine Hydrochloride. Generics contain the same active ingredient as the brand-name original and are usually lower cost.

Is Amantadine Hydrochloride available over the counter?

No. Amantadine Hydrochloride is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.

What forms does Amantadine Hydrochloride come in?

Amantadine Hydrochloride is currently marketed as solution and tablet, per the FDA's National Drug Code Directory.

What class of drug is Amantadine Hydrochloride?

Amantadine Hydrochloride is classified as influenza a m2 protein inhibitor, per the FDA's Established Pharmacologic Class.

Is Amantadine Hydrochloride FDA-registered?

Amantadine Hydrochloride is on record with the U.S. FDA under application number ANDA077992. You can verify this on its official FDA label.