adagen
Adagen (Pegademase Bovine) is a medication used to treat Severe Combined Immunodeficiency.
Pegademase Bovine · by Leadiant Biosci Inc
Key facts
- Active ingredient
- Pegademase Bovine
- Form
- Injectable
- Strength
- Pegademase Bovine 250 UNITS/ML
- Type
- Prescription (Rx)
- Brand or generic
- Brand-name
- May treat
- severe combined immunodeficiency
- Manufacturer
- Leadiant Biosci Inc
- FDA application
- BLA019818
- Availability
- Discontinued (per FDA)
May treat (source: NIH RxClass)
- severe combined immunodeficiency
Dosage forms
Injectable
The forms currently marketed in the U.S., per the FDA National Drug Code Directory.
Ways to save
Ask for the generic
Same active ingredient, far cheaper. Is there a generic? →
Request a 90-day supply
Bulk fills usually lower the per-dose price vs monthly refills.
Use copay cards
Manufacturer copay cards & patient-assistance programs — especially for brand drugs.
Compare alternatives
A same-class option may cost less. See alternatives →
Frequently asked questions
- What does Adagen treat?
- Adagen (Pegademase Bovine) may be used to treat severe combined immunodeficiency, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.
- Is there a coupon or discount for Adagen?
- pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Adagen. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
- Who makes Adagen?
- Adagen is marketed by Leadiant Biosci Inc. You can see Leadiant Biosci Inc's full profile, rating, and other products on pharmaranks.
- Is Adagen a brand-name or generic drug?
- Adagen is a brand-name product with the active ingredient Pegademase Bovine.
- Is Adagen available over the counter?
- No. Adagen is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
- What forms does Adagen come in?
- Adagen is currently marketed as injectable, per the FDA's National Drug Code Directory.
- Is Adagen FDA-registered?
- Adagen is on record with the U.S. FDA under application number BLA019818. You can verify this on its official FDA label.
Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.
What people report to the FDA about PEGADEMASE BOVINE
The FDA Adverse Event Reporting System (FAERS) collects reports from patients and clinicians. It holds 3 reports naming PEGADEMASE BOVINE — the active ingredient in Adagen, and the FDA flagged 100% of those reports as serious. The effects reported most often — leaving out reports about overdose, misuse or the condition being treated, which dominate the raw list for common medicines:
- central nervous system lymphoma1 reports
- deep vein thrombosis1 reports
- erythema nodosum1 reports
- infection1 reports
- pyrexia1 reports
Read these as a signal, not a rate. A report does not mean PEGADEMASE BOVINE caused the effect — anyone can file one, and many describe people taking several medicines for several conditions. Crucially there is no denominator: FAERS does not record how many people took the drug, so these counts cannot be turned into “X% of patients” — a bigger number often just means a more widely used or more talked-about drug. Duplicates exist, and publicity drives reporting. For what is actually established, read the FDA label.
Source: openFDA drug/event (FAERS), retrieved September 25, 2026.
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