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Is insulin aspart safe during pregnancy?

Answered by MotherToBaby’s teratology specialists, quoted in full — including the questions most pages skip, like whether a father’s exposure matters.

By the pharmaranks editorial teamReviewed against the MotherToBaby fact sheet for insulin aspart (OTIS, published via the NIH) sourcesUpdated Jul 21, 2026How we research

The questions people actually ask about insulin aspart in pregnancy

Answered by MotherToBaby, the fact sheets written by the Organization of Teratology Information Specialists and published through the NIH. Quoted in full — we do not condense them.

I take insulin aspart. Can it make it harder for me to get pregnant?

It is not known if insulin aspart can make it harder to get pregnant.

Does taking insulin aspart increase the chance of miscarriage?

Miscarriage is common and can occur in any pregnancy for many different reasons. Taking insulin aspart before or during pregnancy is not expected to increase the chance of miscarriage.

Does taking insulin aspart increase the chance of birth defects?

Birth defects can happen in any pregnancy for different reasons. Out of all babies born each year, about 3 out of 100 (3%) will have a birth defect. We look at research studies to try to understand if an exposure, like insulin aspart, might increase the chance of birth defects in a pregnancy. Insulin aspart is not expected to increase the chance of birth defects.

Does taking insulin aspart in pregnancy increase the chance of other pregnancy-related problems?

No increased chance of pregnancy-related problems, such as preterm delivery (birth before week 37) or low birth weight (weighing less than 5 pounds, 8 ounces [2500 grams] at birth) have been reported with the use of insulin aspart.

Poorly controlled sugar levels can increase the chance of health and pregnancy complications. It is important that your condition is well-treated before, during, and after pregnancy.

Does taking insulin aspart in pregnancy affect future behavior or learning for the child?

It is not known if insulin aspart can increase the chance for behavior or learning issues for the child.

If a man takes insulin aspart, could it affect his fertility or increase the chance of birth defects?

Studies have not been done to see if insulin aspart could affect male fertility (ability to make healthy sperm) or increase the chance of birth defects. In general, exposures that men have are unlikely to increase risks to a pregnancy. For more information, please see the MotherToBaby fact sheet Paternal Exposures at https://mothertobaby.org/fact-sheets/paternal-exposures-pregnancy/ .

Quoted from MotherToBaby Fact Sheets — Insulin Aspart, published March 1, 2026. MotherToBaby states its fact sheets should not take the place of medical care and advice from your healthcare providers.

This is general reference information, not medical advice. Whether to take any medication in pregnancy is a decision for you and your prescriber; do not start or stop a drug on your own, because an untreated condition can also carry risk.