Does plazomicin expire?
The printed date covers the sealed pack. Once plazomicin is opened, mixed or diluted, its label sets a second and usually much shorter limit — quoted below, per product.
Shortest limit on any plazomicin label: 24 hours
“Stability of ZEMDRI Solution in Intravenous Fluids After dilution, ZEMDRI solution for administration is stable for 24 hours at room temperature at concentrations of 2.”
That applies to the product it is printed on, not to every form of plazomicin — check which one you have against the list below.
What the labels say
“Stability of ZEMDRI Solution in Intravenous Fluids After dilution, ZEMDRI solution for administration is stable for 24 hours at room temperature at concentrations of 2.”
On the label for Zemdri (plazomicin) · DailyMed
“Stability of ZEMDRI Solution in Intravenous Fluids After dilution, ZEMDRI solution for administration is stable for 24 hours at room temperature, and for up to 7 days when refrigerated at 2°C to 8°C (36°F to 46°F), at concentrations of 2.”
On the label for Zemdri (plazomicin) · DailyMed
Frequently asked questions
Does plazomicin expire?
Two different clocks apply and only one of them is the printed date. The date on a sealed pack is the manufacturer's guarantee for the unopened product. Once it is opened, mixed or diluted, the label imposes its own limit — as tight as 24 hours on some plazomicin products, and that is the number quoted on this page.
Can I still use plazomicin after the date on the box?
This page cannot tell you that, and nor can any page. The FDA's own shelf-life programme found 88% of tested lots stayed within specification at least a year past expiry — and concluded in the same breath that lot-to-lot variation means this can only be confirmed by testing each lot. What you can check at home is the in-use limit above and whether the product has been stored as the label requires. Ask a pharmacist about a specific pack; they will also dispose of what you no longer need.
Why do different plazomicin products have different limits?
Because they are different formulations. A suspension that gets mixed with water, a pen that gets carried at room temperature, and a sealed tablet do not behave alike, so each manufacturer's label sets its own limit and each is shown here with the product it belongs to. We never merge them into one number for the molecule.
More on plazomicin
Quoted from FDA labels for reference, not medical advice, and not a suggestion to use anything past its limit. If you are unsure whether a pack is still good, a pharmacist can tell you and can dispose of it safely.