Does fosaprepitant dimeglumine expire?
The printed date covers the sealed pack. Once fosaprepitant dimeglumine is opened, mixed or diluted, its label sets a second and usually much shorter limit — quoted below, per product.
Shortest limit on any fosaprepitant dimeglumine label: 24 hours
“The reconstituted final drug solution is stable for 24 hours at ambient room temperature [at or below 25°C (77°F)].”
That applies to the product it is printed on, not to every form of fosaprepitant dimeglumine — check which one you have against the list below.
What the labels say
“The reconstituted final drug solution is stable for 24 hours at ambient room temperature [at or below 25°C (77°F)].”
On the label for FOSAPREPITANT DIMEGLUMINE · DailyMed
“Storage The reconstituted final drug solution is stable for 24 hours at ambient room temperature [at or below 25°C (77°F)].”
On the label for FOSAPREPITANT DIMEGLUMINE · DailyMed
How the label says to keep fosaprepitant dimeglumine
Storage is the other half of the question: the stability behind any date assumes these conditions, and a medicine kept outside them ages faster than the calendar says.
- “16 HOW SUPPLIED/STORAGE AND HANDLING FOCINVEZ (fosaprepitant injection) contains 150 mg/50 mL of fosaprepitant as a clear and colorless ready-to-use injection solution in a single-dose vial.”
- “Refrigerate FOCINVEZ at 2°C to 8°C (36°F to 46°F).”
- “Fosaprepitant for injection vials must be refrigerated, store at 2° to 8°C (36° to 46°F).”
- “The reconstituted final drug solution is stable for 24 hours at ambient room temperature [at or below 25°C (77°F)].”
- “16 HOW SUPPLIED/STORAGE AND HANDLING Single-dose glass vial containing 150 mg of fosaprepitant as a white to off-white lyophilized powder for reconstitution.”
- “Fosaprepitant for Injection vials must be refrigerated, store at 2°C to 8°C (36°F to 46°F).”
- “16 HOW SUPPLIED/STORAGE AND HANDLING Fosaprepitant for injection: Single dose glass vial containing 150 mg of fosaprepitant as a white to off-white lyophilized powder for reconstitution.”
- “Fosaprepitant for injection vials must be refrigerated, store at 2°C to 8°C (36°F to 46°F).”
Frequently asked questions
Does fosaprepitant dimeglumine expire?
Two different clocks apply and only one of them is the printed date. The date on a sealed pack is the manufacturer's guarantee for the unopened product. Once it is opened, mixed or diluted, the label imposes its own limit — as tight as 24 hours on some fosaprepitant dimeglumine products, and that is the number quoted on this page.
Can I still use fosaprepitant dimeglumine after the date on the box?
This page cannot tell you that, and nor can any page. The FDA's own shelf-life programme found 88% of tested lots stayed within specification at least a year past expiry — and concluded in the same breath that lot-to-lot variation means this can only be confirmed by testing each lot. What you can check at home is the in-use limit above and whether the product has been stored as the label requires. Ask a pharmacist about a specific pack; they will also dispose of what you no longer need.
Why do different fosaprepitant dimeglumine products have different limits?
Because they are different formulations. A suspension that gets mixed with water, a pen that gets carried at room temperature, and a sealed tablet do not behave alike, so each manufacturer's label sets its own limit and each is shown here with the product it belongs to. We never merge them into one number for the molecule.
More on fosaprepitant dimeglumine
Quoted from FDA labels for reference, not medical advice, and not a suggestion to use anything past its limit. If you are unsure whether a pack is still good, a pharmacist can tell you and can dispose of it safely.