Technetium Tc-99m Pyrophosphate Kit: uses, dosing, side effects & brands
Technetium Tc-99m Pyrophosphate Kit is a medicine sold in the U.S. under 3 brand and generic names. Below: what the FDA label says, every product that contains it, what the pills look like, and its recall record.
Key facts
- Available as
- Injectable
- Sold as
- 3 products — Technescan Pyp Kit, Cis-Pyro and Phosphotec
- Prescription?
- Prescription only
- Generic available?
- Not in our catalog
How technetium tc-99m pyrophosphate kit is dosed
From the FDA label for Technescan Pyp Kit (application NDA017538). Other technetium tc-99m pyrophosphate kit products — different forms, different strengths — are dosed differently. Follow the label for the one you were prescribed.
Radiation Safety – Drug Handling After radiolabeling of Technescan PYP, the reaction vial contains Technetium Tc 99m Pyrophosphate Injection. Handle Technetium Tc 99m Pyrophosphate Injection with appropriate safety measures to minimize radiation exposure. (See PRECAUTIONS, General .) Use waterproof gloves, effective radiation shielding, and other appropriate safety measures when preparing and handling Technetium Tc 99m Pyrophosphate Injection. Radiopharmaceuticals should be used by or under the control of healthcare providers who are qualified by specific training and experience in the safe use and handling of radionuclides, and whose experience and training have been approved by the appropriate governmental agency authorized to license the use of radionuclides. Recommended Dosage, Administration, and Imaging Instructions for Skeletal and Cardiac Imaging Dosing and Administration Instructions The recommended activity of Technetium Tc 99m Pyrophosphate Injection for each type of imaging is presented in Table 4. Administer Technetium Tc 99m Pyrophosphate Injection intravenously over 10 seconds to 20 seconds. Measure the patient dose with a dose calibrator immediately before administration. If not contraindicated by patient’s condition, encourage patients to drink fluids before and after administration and void as often as possible to reduce unnecessary radiation exposure. For…
Technetium Tc-99m Pyrophosphate Kit side effects
The following adverse reactions associated with the use of Technescan PYP have been reported: flushing, hypotension, fever, chills, nausea, vomiting, and dizziness, as well as hypersensitivity reactions such as itching and various skin rashes.
Who shouldn’t take technetium tc-99m pyrophosphate kit
None known.
Technetium Tc-99m Pyrophosphate Kit drug interactions
The biodistribution of technetium Tc 99m pyrophosphate may be altered in the presence of high levels of certain cations (iron, calcium, and aluminum). This may result in reduced uptake of radionuclide in the skeleton and increased extraosseal uptake, which may potentially degrade imaging quality. In patients with high levels of these cations caused by concomitant medications, particularly patients receiving iron infusions, consider performing an imaging study with technetium Tc 99m pyrophosphate injection once the cation levels have normalized (e.g., after 3 to 5 half-lives of the cation). (See WARNINGS .)
Every technetium tc-99m pyrophosphate kit product we track (3)
Same active ingredient — different manufacturer, form, price and FDA recall record. That last one is what our independent score measures.
| # | Drug | Rating | Type | Form | Generic? | Pharmacy pays | |
|---|---|---|---|---|---|---|---|
| 1 | 70/100 | Prescription | Injectable | No data | — | View → | |
| 2 | Not yet rated | Prescription | Injectable | No data | — | View → | |
| 3 | Not yet rated | Prescription | Injectable | No data | — | View → |
What people report to the FDA about technetium tc-99m pyrophosphate kit
The FDA Adverse Event Reporting System (FAERS) collects reports from patients and clinicians. It holds 7 reports naming technetium tc-99m pyrophosphate kit, and the FDA flagged 29% of those reports as serious. The effects reported most often — leaving out reports about overdose, misuse or the condition being treated, which dominate the raw list for common medicines:
- radioisotope scan abnormal3 reports
- flushing1 reports
- hypersensitivity1 reports
- loss of consciousness1 reports
- nausea1 reports
- paraesthesia oral1 reports
- pruritus1 reports
- rash1 reports
Read these as a signal, not a rate. A report does not mean technetium tc-99m pyrophosphate kit caused the effect — anyone can file one, and many describe people taking several medicines for several conditions. Crucially there is no denominator: FAERS does not record how many people took the drug, so these counts cannot be turned into “X% of patients” — a bigger number often just means a more widely used or more talked-about drug. Duplicates exist, and publicity drives reporting. For what is actually established, read the FDA label section above.
Source: openFDA drug/event (FAERS), retrieved August 26, 2026.
Related calculators
Frequently asked questions
What is technetium tc-99m pyrophosphate kit?
Drug Characteristics Technescan™ PYP™ (kit for the preparation of technetium Tc 99m pyrophosphate injection) is a radioactive diagnostic drug for intravenous use after radiolabeling with sodium pertechnetate Tc 99m injection or after reconstitution with 0.9% sodium chloride injection in conjunction with sodium pertechnetate Tc 99m injection. Each vial contains 11.9 mg sodium pyrophosphate, 3.2 mg (minimum) stannous chloride (SnCl 2 •2H 2 O), and 4.4 mg (maximum) total tin expressed as stannous chloride (SnCl 2 •2H 2 O). Prior to lyophilization, the pH is adjusted with hydrochloric acid. The pH of the reconstituted drug is between 4.5 and 7.5. No bacteriostatic preservative is present. The vial contains a sterile, non-pyrogenic, lyophilized powder packaged under nitrogen. The precise structures of the stannous-pyrophosphate and technetium Tc 99m pyrophosphate complexes are not known.
Can you take technetium tc-99m pyrophosphate kit with other medicines?
It depends on the medicine. We check it against the FDA labels rather than guessing: our interaction checker searches each drug's own label for the other and quotes what it says, naming the section it came from. Run technetium tc-99m pyrophosphate kit against whatever else you take — and remember that a label not naming a drug is not the same as that combination being safe.
What brand names is technetium tc-99m pyrophosphate kit sold under?
We track 3 technetium tc-99m pyrophosphate kit-containing products in the U.S.: Technescan Pyp Kit, Cis-Pyro and Phosphotec. They are the same active ingredient; they differ in form, manufacturer, price and FDA recall record.
What forms does technetium tc-99m pyrophosphate kit come in?
Across the brands we track, technetium tc-99m pyrophosphate kit is currently marketed as injectable, per the FDA's National Drug Code Directory. Each form is dosed differently — follow the label for the exact product you were prescribed.
Is there a generic technetium tc-99m pyrophosphate kit?
We do not currently list a generic-labelled technetium tc-99m pyrophosphate kit product. That does not always mean none exists — it means none appears under a generic name in the FDA data we track. Ask your pharmacist.
Cite this page
- APA
- pharmaranks. (2026, July 24). Technetium Tc-99m Pyrophosphate Kit: uses, dosing, side effects & brands. https://pharmaranks.com/drugs/technetium-tc-99m-pyrophosphate-kit
- MLA
- “Technetium Tc-99m Pyrophosphate Kit: uses, dosing, side effects & brands.” pharmaranks, 24 July 2026, https://pharmaranks.com/drugs/technetium-tc-99m-pyrophosphate-kit.
We summarise public FDA and NIH sources — for a clinical claim, cite the primary source we link to as well.
Sources: FDA openFDA drug label, National Drug Code Directory, and Enforcement (recall) database. This page reproduces public FDA data and is not medical advice. Dosing is set by your prescriber.
Read the full FDA label for technetium tc-99m pyrophosphate kit on DailyMed (NIH) ↗.