Technetium Tc-99m Pertechnetate Generator: uses, dosing, side effects & brands

The Ultra-Technekow ™ V4 Generator is prepared with fission-produced molybdenum Mo-99 adsorbed onto alumina in a column shielded by lead, tungsten, or depleted uranium. The column assembly and shielding are encased in a plastic container that is covered with a plastic elution hood. The elution hood has an opening for the column assembly double inlet needles and an opening for the single outlet needle. The needles accommodate the sterile eluant vials that contain 0.9% Sodium Chloride Injection and sterile evacuated collection vials. A sterile vial containing a bacteriostat is supplied with the generator for the customer to aseptically seal the outlet needle after each elution. This terminally sterilized generator provides a closed system for the production of sterile metastable technetium Tc-99m, which is produced by the decay of molybdenum Mo-99. Incorporated between the column outlet and the collection vial is a sterile 0.22 micrometer filter. Sterile, non-pyrogenic isotonic solutions of Sodium Pertechnetate Tc 99m Injection in 0.9% Sodium Chloride Injection can be obtained conveniently by periodic aseptic elution of the generator. These solutions should be clear, colorless, and free from any particulate matter. The Sodium Pertechnetate Tc 99m Injection is suitable for intravenous injection and direct instillation. The carrier-free solution may be used as is, or diluted to…

It depends on the medicine. We check it against the FDA labels rather than guessing: our interaction checker searches each drug's own label for the other and quotes what it says, naming the section it came from. Run technetium tc-99m pertechnetate generator against whatever else you take — and remember that a label not naming a drug is not the same as that combination being safe.

We track 4 technetium tc-99m pertechnetate generator-containing products in the U.S.: Ultra-Technekow V4, Drytec, Minitec and Technelite. They are the same active ingredient; they differ in form, manufacturer, price and FDA recall record.

Across the brands we track, technetium tc-99m pertechnetate generator is currently marketed as injectable and solution, per the FDA's National Drug Code Directory. Each form is dosed differently — follow the label for the exact product you were prescribed.

We do not currently list a generic-labelled technetium tc-99m pertechnetate generator product. That does not always mean none exists — it means none appears under a generic name in the FDA data we track. Ask your pharmacist.