Technetium Tc-99m Mebrofenin Kit: uses, dosing, side effects & brands
Technetium Tc-99m Mebrofenin Kit is a medicine sold in the U.S. under one brand. Below: what the FDA label says, every product that contains it, what the pills look like, and its recall record.
Key facts
- Available as
- Injectable
- Sold as
- Choletec
- Prescription?
- Prescription only
- Generic available?
- Not in our catalog
How technetium tc-99m mebrofenin kit is dosed
From the FDA label for Choletec (application NDA018963). Other technetium tc-99m mebrofenin kit products — different forms, different strengths — are dosed differently. Follow the label for the one you were prescribed.
The suggested intravenous dose range of Technetium Tc 99m Mebrofenin in the average patient (70 kg) is: Nonjaundiced patient: 74-185 MBq (2-5 mCi) Patient with serum bilirubin level greater than 1.5 mg/dL: 111-370 MBq (3-10 mCi) The patient dose should be measured by a suitable radioactivity calibration system immediately prior to administration. The patient should be in a fasting state, 4 hours is preferable. False positives (non-visualization) may result if the gallbladder has been emptied by ingestion of food. An interval of at least 24 hours should be allowed before repeat examination. Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration whenever solution and container permit.
Technetium Tc-99m Mebrofenin Kit side effects
Urticaria and rash have been rarely reported with the use of Technetium Tc 99m Mebrofenin since market introduction. Rare cases of chills and nausea have been reported with related compounds. Infrequently, death has been reported in association with the use of this class of agents.
Who shouldn’t take technetium tc-99m mebrofenin kit
Hypersensitivity to this compound.
Every technetium tc-99m mebrofenin kit product we track (1)
Same active ingredient — different manufacturer, form, price and FDA recall record. That last one is what our independent score measures.
Only one: Choletec.
What people report to the FDA about technetium tc-99m mebrofenin kit
The FDA Adverse Event Reporting System (FAERS) collects reports from patients and clinicians. It holds 12 reports naming technetium tc-99m mebrofenin kit, and the FDA flagged 33% of those reports as serious. The effects reported most often — leaving out reports about overdose, misuse or the condition being treated, which dominate the raw list for common medicines:
- dizziness3 reports
- urticaria3 reports
- balance disorder2 reports
- confusional state2 reports
- coordination abnormal2 reports
- disorientation2 reports
- disturbance in attention2 reports
- erythema2 reports
Read these as a signal, not a rate. A report does not mean technetium tc-99m mebrofenin kit caused the effect — anyone can file one, and many describe people taking several medicines for several conditions. Crucially there is no denominator: FAERS does not record how many people took the drug, so these counts cannot be turned into “X% of patients” — a bigger number often just means a more widely used or more talked-about drug. Duplicates exist, and publicity drives reporting. For what is actually established, read the FDA label section above.
Source: openFDA drug/event (FAERS), retrieved July 26, 2026.
Related calculators
Frequently asked questions
What is technetium tc-99m mebrofenin kit?
Each reaction vial contains a nonradioactive, sterile, nonpyrogenic mixture of 45 mg mebrofenin, 0.54 mg (minimum) stannous fluoride dihydrate, SnF 2 •2H 2 O and 1.03 mg total tin, maximum (as stannous fluoride dihydrate, SnF 2 •2H 2 O), not more than 5.2 mg methylparaben, and 0.58 mg propylparaben. The pH is adjusted with sodium hydroxide or hydrochloric acid prior to lyophilization. The contents of the vial are lyophilized and sealed under nitrogen at the time of manufacture. The pH of the reconstituted product is 4.2 to 5.7. The structure of mebrofenin (2,2’-[[2-[(3-Bromo-2,4,6-trimethylphenyl)-amino]-2-oxoethyl]imino] bisacetic acid) is shown below: When sterile, pyrogen-free sodium pertechnetate Tc 99m injection is added to the vial, the diagnostic agent Technetium Tc 99m Mebrofenin is formed for administration by intravenous injection. Choletec-struct
Can you take technetium tc-99m mebrofenin kit with other medicines?
It depends on the medicine. We check it against the FDA labels rather than guessing: our interaction checker searches each drug's own label for the other and quotes what it says, naming the section it came from. Run technetium tc-99m mebrofenin kit against whatever else you take — and remember that a label not naming a drug is not the same as that combination being safe.
What forms does technetium tc-99m mebrofenin kit come in?
Across the brands we track, technetium tc-99m mebrofenin kit is currently marketed as injectable, per the FDA's National Drug Code Directory. Each form is dosed differently — follow the label for the exact product you were prescribed.
Is there a generic technetium tc-99m mebrofenin kit?
We do not currently list a generic-labelled technetium tc-99m mebrofenin kit product. That does not always mean none exists — it means none appears under a generic name in the FDA data we track. Ask your pharmacist.
Cite this page
- APA
- pharmaranks. (2026, July 24). Technetium Tc-99m Mebrofenin Kit: uses, dosing, side effects & brands. https://pharmaranks.com/drugs/technetium-tc-99m-mebrofenin-kit
- MLA
- “Technetium Tc-99m Mebrofenin Kit: uses, dosing, side effects & brands.” pharmaranks, 24 July 2026, https://pharmaranks.com/drugs/technetium-tc-99m-mebrofenin-kit.
We summarise public FDA and NIH sources — for a clinical claim, cite the primary source we link to as well.
Sources: FDA openFDA drug label, National Drug Code Directory, and Enforcement (recall) database. This page reproduces public FDA data and is not medical advice. Dosing is set by your prescriber.
Read the full FDA label for technetium tc-99m mebrofenin kit on DailyMed (NIH) ↗.