Selpercatinib: uses, dosing, side effects & brands
Selpercatinib is a medicine sold in the U.S. under one brand. Below: what the FDA label says, every product that contains it, what the pills look like, and its recall record.
Key facts
- Available as
- Capsule · Tablet
- Sold as
- Retevmo
- Prescription?
- Prescription only
- Generic available?
- Not in our catalog
Every selpercatinib product we track (1)
Same active ingredient — different manufacturer, form, price and FDA recall record. That last one is what our independent score measures.
Only one: Retevmo.
What selpercatinib pills look like
Imprint codes, colour and shape from the FDA’s labelling data. Match the imprint on your pill — or search any imprint.
| Imprint | Strength | Colour | Shape | Maker |
|---|---|---|---|---|
| Lilly;3977;40mg | 40 mg | gray | capsule | — |
| Lilly;2980;80mg | 80 mg | blue | capsule | — |
| Ret40;5340 | 40 mg | gray | round | — |
| Ret80;6082 | 80 mg | purple | round | — |
| Ret120;6120 | 120 mg | purple | round | — |
| Ret160;5562 | 160 mg | pink | round | — |
Can you crush or split selpercatinib?
At least one selpercatinibproduct is labelled to be swallowed whole — crushing an extended-release tablet releases the whole day’s dose at once. Which applies depends on the form you were given.
What each selpercatinib label says about crushing, splitting and chewingWhat people report to the FDA about selpercatinib
The FDA Adverse Event Reporting System (FAERS) collects reports from patients and clinicians. It holds 357 reports naming selpercatinib, and the FDA flagged 96% of those reports as serious. The effects reported most often — leaving out reports about overdose, misuse or the condition being treated, which dominate the raw list for common medicines:
- malignant neoplasm progression61 reports
- diarrhoea32 reports
- blood creatinine increased24 reports
- hypertension24 reports
- fatigue23 reports
- thrombocytopenia20 reports
- alanine aminotransferase increased19 reports
- aspartate aminotransferase increased19 reports
Read these as a signal, not a rate. A report does not mean selpercatinib caused the effect — anyone can file one, and many describe people taking several medicines for several conditions. Crucially there is no denominator: FAERS does not record how many people took the drug, so these counts cannot be turned into “X% of patients” — a bigger number often just means a more widely used or more talked-about drug. Duplicates exist, and publicity drives reporting. For what is actually established, read the FDA label.
Source: openFDA drug/event (FAERS), retrieved September 26, 2026.
Related calculators
Frequently asked questions
Can you take selpercatinib with other medicines?
It depends on the medicine. We check it against the FDA labels rather than guessing: our interaction checker searches each drug's own label for the other and quotes what it says, naming the section it came from. Run selpercatinib against whatever else you take — and remember that a label not naming a drug is not the same as that combination being safe.
What forms does selpercatinib come in?
Across the brands we track, selpercatinib is currently marketed as capsule and tablet, per the FDA's National Drug Code Directory. Each form is dosed differently — follow the label for the exact product you were prescribed.
Is there a generic selpercatinib?
We do not currently list a generic-labelled selpercatinib product. That does not always mean none exists — it means none appears under a generic name in the FDA data we track. Ask your pharmacist.
Cite this page
- APA
- pharmaranks. (2026, July 24). Selpercatinib: uses, dosing, side effects & brands. https://pharmaranks.com/drugs/selpercatinib
- MLA
- “Selpercatinib: uses, dosing, side effects & brands.” pharmaranks, 24 July 2026, https://pharmaranks.com/drugs/selpercatinib.
We summarise public FDA and NIH sources — for a clinical claim, cite the primary source we link to as well.
Sources: FDA openFDA drug label, National Drug Code Directory, and Enforcement (recall) database. This page reproduces public FDA data and is not medical advice. Dosing is set by your prescriber.
Read the full FDA label for selpercatinib on DailyMed (NIH) ↗.