Probenecid: uses, dosing, side effects & brands
Probenecid is a medicine sold in the U.S. under one brand. Below: what the FDA label says, every product that contains it, what the pills look like, and its recall record.
Key facts
- Available as
- Tablet
- Sold as
- Probenecid
- Prescription?
- Prescription only
- Generic available?
- Yes
- What the pharmacy pays
- about $20 for a 30-count supply — not your price
Every probenecid product we track (1)
Same active ingredient — different manufacturer, form, price and FDA recall record. That last one is what our independent score measures.
Only one: Probenecid.
What probenecid pills look like
Imprint codes, colour and shape from the FDA’s labelling data. Match the imprint on your pill — or search any imprint.
Combination products containing probenecid
A combination is a different drug — different dosing, different warnings. It is listed here so you can find it, not so you can substitute it.
How long probenecid keeps
No probenecid label we read sets a separate limit for after opening, but they do specify how it must be stored — and the stability behind any date assumes those conditions.
Does probenecid expire? The in-use limits and storage rules from its labelsProbenecid and breastfeeding
From LactMed, the US National Library of Medicine’s Drugs and Lactation Database — quoted, not rewritten.
Full LactMed record for probenecid: levels in milk, effects in breastfed infants, and the drugs it would consider insteadLimited information indicates that maternal doses of probenecid up to 2 grams daily produce low levels in milk and would not be expected to cause any adverse effects in breastfed infants, especially if the infant is older than 2 months. In animal studies, probenecid increased the breastmilk excretion of cimetidine, possible via an interaction with an active transport mechanism in the breast. The implications of enhanced excretion of drugs given with probenecid for nursing mothers and their infants has not been studied; however, only a few drugs are known to undergo active transport into breastmilk.
National Institute of Child Health and Human Development, record revised July 19, 2021. LactMed states its information is not a substitute for professional judgement.
What people report to the FDA about probenecid
The FDA Adverse Event Reporting System (FAERS) collects reports from patients and clinicians. It holds 1,436 reports naming probenecid, and the FDA flagged 72% of those reports as serious. The effects reported most often — leaving out reports about overdose, misuse or the condition being treated, which dominate the raw list for common medicines:
- diarrhoea125 reports
- nausea64 reports
- vomiting61 reports
- asthenia60 reports
- fatigue60 reports
- dyspnoea57 reports
- headache52 reports
- dizziness50 reports
Read these as a signal, not a rate. A report does not mean probenecid caused the effect — anyone can file one, and many describe people taking several medicines for several conditions. Crucially there is no denominator: FAERS does not record how many people took the drug, so these counts cannot be turned into “X% of patients” — a bigger number often just means a more widely used or more talked-about drug. Duplicates exist, and publicity drives reporting. For what is actually established, read the FDA label section above.
Source: openFDA drug/event (FAERS), retrieved July 26, 2026.
Related calculators
Frequently asked questions
Can you take probenecid with other medicines?
It depends on the medicine. We check it against the FDA labels rather than guessing: our interaction checker searches each drug's own label for the other and quotes what it says, naming the section it came from. Run probenecid against whatever else you take — and remember that a label not naming a drug is not the same as that combination being safe.
What forms does probenecid come in?
Across the brands we track, probenecid is currently marketed as tablet, per the FDA's National Drug Code Directory. Each form is dosed differently — follow the label for the exact product you were prescribed.
Is there a generic probenecid?
Yes. Our catalog lists 1 generic probenecid product alongside the brand versions. A generic has the same active ingredient and must meet the FDA's bioequivalence standard; it usually costs less. Ask your pharmacist which one your plan covers.
Cite this page
- APA
- pharmaranks. (2026, July 24). Probenecid: uses, dosing, side effects & brands. https://pharmaranks.com/drugs/probenecid
- MLA
- “Probenecid: uses, dosing, side effects & brands.” pharmaranks, 24 July 2026, https://pharmaranks.com/drugs/probenecid.
We summarise public FDA and NIH sources — for a clinical claim, cite the primary source we link to as well.
Sources: FDA openFDA drug label, National Drug Code Directory, and Enforcement (recall) database. This page reproduces public FDA data and is not medical advice. Dosing is set by your prescriber.
Read the full FDA label for probenecid on DailyMed (NIH) ↗.